Abstract
The purpose of this study was to investigate the frequency of allergy in 85 families of pediatric patients with asthma and/or rhinitis. Families enrolled were drawn according to a table of randomization, from those whose children were referred the outpatient clinic of the Pulmonology Department of Gaslini Institute (Genoa, Italy). In patients and in both their mothers and fathers, allergic sensitization to the three most common classes of inhalant allergens (house dust mites, pollens, and animal danders) was evaluated by skin prick test. As compared with their parents, children showed a similar prevalence of positive skin prick test (50.0% and 58.8%, respectively; chi 2 = 1.4; P > .1), but a significantly higher frequency of specific sensitization to house dust mites, pollens, or pets (P < .05, each chi 2). These differences were at least partially related to the higher frequency of polysensitization (i.e., sensitization to more than one class of allergens) in children than in their parents [chi 2 = 4.2, odds ratio (OR) = 2.3, 95% confidence interval (CI95%) = 1.0 to 5.1; P < .05). In addition, both in children (chi 2 = 5.8, OR = 11.3, CI95% = 1.4 to 81.5; P < .05] and in their parents (chi 2 = 7.4, OR = 4.8, CI95% = 1.5 to 16....Continue Reading
References
Sep 1, 1976·Acta paediatrica Scandinavica·N I Kjellman, S G Johansson
Apr 4, 1992·BMJ : British Medical Journal·T K Ninan, G Russell
Feb 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R P YoungJ M Hopkin
Jan 1, 1991·Immunogenetics·A A AnsariD G Marsh
Jun 10, 1989·Lancet·W O CooksonJ M Hopkin
Nov 1, 1989·Acta paediatrica Scandinavica·L Pöysä
Jan 1, 1988·Allergy·O Zetterström
Jan 1, 1988·Allergy·N I Kjellman
Jul 1, 1987·The American Review of Respiratory Disease
Jan 19, 1985·British Medical Journal·K M VenablesA J Taylor
Jul 1, 1985·The Journal of Allergy and Clinical Immunology·A B MurrayB J Morrison
Sep 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·D G MarshK Ishizaka
Jan 1, 1972·The Journal of Pediatrics·M L Lubs
Feb 1, 1984·The Journal of Allergy and Clinical Immunology·R J HoppR G Townley
Jul 1, 1983·Allergy·R LuomaM Viander
May 1, 1982·The Journal of Experimental Medicine·D G MarshW B Bias
Jan 1, 1982·Clinical Allergy·K K Eaton
Jan 1, 1982·International Archives of Allergy and Applied Immunology·R Happle, U W Schnyder
Sep 1, 1980·Clinical Allergy·F BjörksténV Koski
Jul 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J KuehrK Weiss
Mar 1, 1996·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·M SilvestriP Crimi
Jul 1, 1996·The Journal of Allergy and Clinical Immunology·D Diaz-SanchezA Saxon
Citations
Apr 20, 2006·Lung·Eugene YangKyu-Earn Kim
Nov 30, 2005·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Young YooYoung Yull Koh
May 19, 2000·Thorax·M SilvestriG A Rossi
Oct 20, 2001·Thorax·M SilvestriG A Rossi
Apr 20, 2001·Proceedings of the National Academy of Sciences of the United States of America·H Mori, K Ito
Jul 7, 2015·Expert Review of Clinical Immunology·Giorgio CiprandiUNKNOWN Italian Study Group on Polysensitization
Nov 15, 2011·European Journal of Internal Medicine·Giorgio Ciprandi, Ignazio Cirillo
Jun 23, 2005·Allergy·H KangY Y Koh
Dec 17, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Oliviero SaccoGiovanni A Rossi
Jul 17, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Adriana Baatenburg de JongPaul L P Brand
May 7, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Tmirah HaselkornUNKNOWN TENOR Study Group
Oct 19, 2004·Medical Hypotheses·Adriano Mari
Apr 12, 2011·Expert Opinion on Biological Therapy·Giorgio CiprandiFranco Frati
Mar 6, 2013·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Cindy M A de BotHeleen Moed
Nov 28, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Giorgio CiprandiGiorgio Walter Canonica
Apr 7, 2017·Allergy & Rhinology·Angelo G CorsicoGiorgio Ciprandi
Nov 21, 2001·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·D SpallarossaG A Rossi
May 16, 2008·Allergologia et immunopathologia·F ErelM Karaayvaz
Mar 9, 2021·Frontiers in Immunology·Priya J SarateUrsula Wiedermann