Frequency, cost, and risk factors of readmissions among severe sepsis survivors

Critical Care Medicine
Andrew J GoodwinDee W Ford

Abstract

To determine the frequency, mortality, cost, and risk factors associated with readmission after index hospitalization with severe sepsis. Observational cohort study of Healthcare Cost and Utilization Project data. All nonfederal hospitals in three U.S. states. Severe sepsis survivors (n = 43,452) in the first two quarters of 2011. None. We measured readmission rates and the associated cost and mortality of readmissions in severe sepsis survivors. We used multivariable logistic regression to identify patient and hospitalization characteristics associated with readmission. Of 43,452 sepsis survivors, 26% required readmission within 30 days and 48% within 180 days. The cumulative mortality rate of sepsis survivors attributed to readmissions was 8%, and the estimated cost was over $1.1 billion. Among survivors, 25% required multiple readmissions within 180 days and accounted for 77% of all readmissions. Age younger than 80 years (odds ratio, 1.14; 95% CI, 1.08-1.21), black race (odds ratio, 1.18; 95% CI, 1.10-1.26), and Medicare or Medicaid payor status (odds ratio, 1.21; 95% CI, 1.13-1.30; odds ratio, 1.34; 95% CI, 1.23-1.46, respectively) were associated with greater odds of 30-day readmission while female gender was associated w...Continue Reading

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