Frequency dependent corticofugal excitation of principal cells in the cat's dorsal lateral geniculate nucleus

Experimental Brain Research
Sivert Lindström, Andrzej Wróbel

Abstract

Excitatory postsynaptic potentials (EPSPs) were evoked in principal cells of the cat's dorsal lateral geniculate nucleus by electrical stimulation of cortico-geniculate fibres. The EPSPs had a pronounced frequency sensitivity. They were barely detectable at stimulation frequencies below 3 Hz but increased dramatically in size at higher frequencies. At 30-50 Hz their amplitude typically exceeded that of EPSPs from optic tract fibres. A prominent EPSP potentiation was also obtained with pair pulse stimulation. The findings are discussed in relation to the hypothesis that the cortico-geniculate system serves as a variable gain regulator for the visual input to the cortex.

References

Mar 1, 1977·Journal of Neurophysiology·M W Dubin, B G Cleland
Sep 1, 1975·The Journal of Comparative Neurology·C D Gilbert, J P Kelly
Jun 1, 1983·Acta Physiologica Scandinavica·G Ahlsén, S Lindström
Jul 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·F Crick
Sep 1, 1983·The Journal of Physiology·D Ferster, S Lindström
May 1, 1983·The Journal of Comparative Neurology·J A Robson
Mar 25, 1982·Brain Research·G Ahlsén, S Lindström
Jun 28, 1954·The Journal of Physiology·J DEL CASTILLO, B KATZ

❮ Previous
Next ❯

Citations

Dec 4, 2010·Pflügers Archiv : European journal of physiology·Sivert Lindström, Andrzej Wróbel
Aug 1, 1994·Current Opinion in Neurobiology·D A McCormick, T Bal
May 3, 2002·Neuroscience Research·Takeshi Kaneko, Fumino Fujiyama
May 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·M SteriadeG Oakson
Apr 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·D A McCormick, M von Krosigk
Jan 21, 1997·Proceedings of the National Academy of Sciences of the United States of America·C Pedroarena, R Llinás
Mar 29, 2001·Proceedings of the National Academy of Sciences of the United States of America·P GolshaniE G Jones
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Bernice PorjeszHenri Begleiter
May 22, 2013·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Mateusz GolaAndrzej Wróbel
May 14, 2004·Journal of Neurophysiology·Iva Reichova, S Murray Sherman
Jan 5, 2005·Molecular Psychiatry·P García-Junco-ClementeR Fernández-Chacón
Dec 17, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R LlinásC Pedroarena
Mar 4, 2003·Journal of Neurophysiology·Björn Granseth, Sivert Lindström
Aug 2, 2003·Journal of Neurophysiology·Jianli LiMartha E Bickford
Apr 20, 2011·The Journal of Physiology·Sigita AugustinaitePaul Heggelund
Aug 11, 2015·The Journal of Physiology·Maxim Nikolaev, Paul Heggelund
May 29, 2020·Proceedings of the National Academy of Sciences of the United States of America·Megan A KirchgessnerEdward M Callaway
Jun 6, 2009·The Journal of Comparative Neurology·Sean P MastersonMartha E Bickford
Dec 12, 2019·Proceedings of the National Academy of Sciences of the United States of America·Geancarlo ZanattaB A Wallace

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.