Frequency, impact, and predictors of persistent pain after root canal treatment: a national dental PBRN study

Pain
Donald R NixdorfNational Dental PBRN Collaborative Group

Abstract

Root canal treatment (RCT) is commonly performed surgery and persistent pain is known to occur, but little is known about how these patients are affected by this pain. Although biopsychosocial mechanisms are thought to be associated with the development of such pain, similar to persistent pain after surgery in other body sites, little is known about the baseline predictors for persistent pain. We assessed the frequency of persistent pain 6 months after RCT, measured the impact this pain had on patients, and determined predictive factors for persistent tooth pain in a multicenter prospective cohort study conducted within the National Dental Practice-Based Research Network. Of 708 patients enrolled, 651 (91.9%) provided follow-up data, with 65 (10.0%) meeting criteria for pain 6 months after RCT. On average, these patients reported their pain as mild to moderate in intensity, present for approximately 10 days in the preceding month, and minimally interfered with daily activities. After adjusting for the type of dental practitioner and patient age, gender, and household income, pain duration over the week before RCT significantly increased the risk of developing persistent pain (odds ratio = 1.19 per 1 day increase in pain duratio...Continue Reading

Associated Clinical Trials

Sep 14, 2010·Gregg H. Gilbert, DDS, MBA, FAAHD

References

Aug 1, 1992·Pain·Michael Von KorffSamuel F Dworkin
Jan 1, 1997·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·L LeResche
May 16, 2006·Lancet·Henrik KehletClifford J Woolf
Dec 19, 2006·Journal of Endodontics·Stephen CohenJay S Kim
Jan 3, 2008·The Journal of the American Dental Association·Gregg H GilbertUNKNOWN DPBRN Collaborative Group
Apr 25, 2008·British Journal of Anaesthesia·W A Macrae
Apr 1, 2010·BMC Medicine·Susan MallettDouglas G Altman
Aug 24, 2010·Journal of Endodontics·Donald R NixdorfMike T John
Aug 19, 2011·Journal of Oral Rehabilitation·D R NixdorfUNKNOWN International RDC-TMD Consortium
Jul 31, 2012·International Orthopaedics·Spencer S LiuThomas P Sculco
Sep 18, 2012·Journal of Endodontics·Victoria Soo Hoon YuChin-ying Stephen Hsu
Oct 16, 2012·Journal of Endodontics·Donald R NixdorfUNKNOWN National Dental PBRN Collaborative Group
Dec 20, 2012·National Journal of Maxillofacial Surgery·Rakesh Kumar YadavKulwinder Kaur Wadhwani
Apr 20, 2013·Journal of Dentistry·Gregg H GilbertUNKNOWN National Dental PBRN Collaborative Group
May 14, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·M ArtusH Beloeil
Jul 1, 2014·Psychosomatic Medicine·Lynn V DoeringMichael R Irwin

❮ Previous
Next ❯

Citations

Apr 28, 2016·Journal of Endodontics·Maria PiggUNKNOWN National Dental Practice-Based Research Network Collaborative Group
Apr 21, 2017·Cephalalgia : an International Journal of Headache·Rafael Benoliel, Charly Gaul
Dec 5, 2019·Oral Diseases·Alberto Herrero BabiloniEstephan J Moana-Filho
Feb 19, 2020·Scientific Reports·Heather Lynn RossiIshmail Abdus-Saboor
Jun 27, 2019·European Journal of Pain : EJP·Ozge ErdoganJennifer L Gibbs
May 16, 2019·Journal of Dental Research·L VaseM Pigg
May 18, 2020·Social Science & Medicine·Lindsay R WilkinsonRenae Wilkinson
Dec 4, 2020·Journal of Endodontics·Ali NosratAlan S Law
Feb 21, 2021·Journal of Endodontics·Anita AminoshariaeKenneth M Hargreaves
Apr 9, 2021·Anesthesiology·Mark D WillinghamSimon Haroutounian
Jun 3, 2021·International Journal of Molecular Sciences·Yi YeJennifer Gibbs
Jul 9, 2021·Scientific Reports·Nayane Chagas Carvalho AlvesDiana Santana de Albuquerque
Oct 9, 2021·Clinical and Experimental Dental Research·Ozge ErdoganLorel E Burns
Sep 18, 2020·Journal of Endodontics·Ahmed A AlelyaniAnibal Diogenes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.