Frequency of Alzheimer's neurofibrillary tangles in the basal ganglia and brain-stem in Alzheimer's disease, senile dementia and the aged

Folia Psychiatrica Et Neurologica Japonica
H Ishino, S Otsuki

Abstract

The authors studied the frequency of neurofibrillary tangles in the basal ganglia and brain-stem of two cases with Alzheimer's disease (average 55 years of age), six cases with senile dementia (average 82 years) and ten cases with cerebral softening and arteriosclerosis in old age (average 79 years). The distribution pattern of ANC was almost the same in Alzheimer's disease and senile dementia, i.e. plenty of ANC were found in the nucl. dorsalis raphe, nucl. centralis superior, nucl. mamilloinfundibularis and nucl. basilaris, but in senile dementia ANC were much fewer in the thalamus and lenticular nuclei. In the aged with cerebral softening and arteriosclerosis, a negligible number of ANC in the brain-stem made a marked contrast to a large quantity of ANC in the cases with senile dementia. Hence, as far as ANC in the brain-stem is concerned, no continuum seems to exist between normal senility and senile dementia.

References

Jan 1, 1971·Acta Neuropathologica·K Jellinger
Jan 1, 1966·Acta Neurologica Scandinavica·A Torvik, D Meen

❮ Previous
Next ❯

Citations

Jan 1, 1983·Journal of Neurology·A JonesB A Thompkins-Ober
Jan 1, 1985·Acta Neuropathologica·T Yamamoto, A Hirano
Oct 27, 1995·Mechanisms of Ageing and Development·R Giess, W Schlote
Jan 2, 1989·Neuroscience Letters·T G Ohm, H Braak
Dec 24, 2008·Journal of Neuropathology and Experimental Neurology·Peter T NelsonWilliam R Markesbery
Dec 22, 1978·Radiation and Environmental Biophysics·J H MerrittS J Allen
Mar 1, 1981·Diabetologia·Jana HavrankovaJ Roth
Nov 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·T ErikssonS Edén
Oct 1, 1980·Naunyn-Schmiedeberg's Archives of Pharmacology·T Eriksson, A Carlsson
Jan 13, 2018·Frontiers in Human Neuroscience·Luca Falciati, Claudio Maioli
Feb 24, 2001·Annals of Neurology·J ParviziA Damasio
Mar 7, 2021·International Journal of Molecular Sciences·Yu-Jung ChengHsien-Yuan Lane

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.