PMID: 16501811Feb 28, 2006Paper

Frequency of CCR5delta32 in Brazilian populations

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
A E VargasJ A B Chies

Abstract

A sample of 103 randomly chosen healthy individuals from Alegrete, RS, Brazil, was tested for the CCR5delta32 allele, which is known to influence susceptibility to HIV-1 infection. The CCR5delta32 allele was identified by PCR amplification using specific primers flanking the region of deletion, followed by electrophoresis on a 3% agarose gel. The data obtained were compared to those reported for other populations and interpreted in terms of Brazilian history. The individuals studied came from a highly admixed population. Most of them were identified as white (N = 59), while blacks and browns (mulattoes) were N = 13 and N = 31, respectively. The observed frequencies, considering the white, black and brown samples (6.8, 3.8, and 6.4%, respectively), suggest an important European parental contribution, even in populations identified as black and brown. However, in Brazil as a whole, this allele shows gradients indicating a relatively good correlation with the classification based on skin color and other physical traits, used here to define major Brazilian population groups.

References

Jul 10, 1998·Immunology Letters·G A Passos, V P Picanço
Jan 18, 2003·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A B Chies, M H Hutz
Oct 10, 2003·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Patrícia MuneratoRicardo Sobhie Diaz
Nov 5, 2003·American Journal of Human Biology : the Official Journal of the Human Biology Council·Sidia M Callegari-JacquesMara H Hutz
Jun 28, 2005·American Journal of Human Biology : the Official Journal of the Human Biology Council·Tabita HünemeierJosé A B Chies

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Citations

May 1, 2013·Human Immunology·Catarina AddobbatiPaula Sandrin-Garcia
Jul 1, 2009·Genetics and Molecular Biology·Ana L Miranda-VilelaMaria N Klautau-Guimarães
Apr 29, 2014·Archives of Gynecology and Obstetrics·Bianca TeliniPriscila Vianna
Mar 6, 2016·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·André de Lima Guerra CoradoFelipe Gomes Naveca
Sep 8, 2011·International Journal of Immunogenetics·R SchreiberW Nadruz
Jun 19, 2013·International Journal of Immunogenetics·A PontilloS Crovella
Dec 31, 2014·Disease Markers·Mariana Pezzute LopesMaria de Fátima Sonati
Jan 7, 2014·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·G K da SilvaJosé Artur Bogo Chies
Jun 19, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Alessandra PontilloAna Carla Pereira
Apr 7, 2012·Genetics and Molecular Biology·Josileide Duarte de FariasVera Engracia
Mar 26, 2009·Lupus·T MucenicR M Xavier
Jan 10, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Alessandra PontilloAlberto J S Duarte
Jul 9, 2011·Memórias do Instituto Oswaldo Cruz·Valdimara Corrêa VieiraAna Maria Barral de Martínez
Jan 15, 2014·Molecular Biology Reports·Jaqueline De Azevêdo SilvaPaula Sandrin-Garcia
Mar 20, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Alessandra PontilloSergio Crovella
Mar 27, 2020·International Journal of Immunogenetics·Joel Henrique EllwangerJosé Artur Bogo Chies
May 23, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Sylvia Lopes Maia TeixeiraMariza Gonçalves Morgado

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