Frequency of Helicobacter pylori and cytotoxine associated gene A antibodies in patients with cardiac syndrome X.

Journal of Cardiovascular Disease Research
Yousef Rasmi, Mir-Hossein Seyyed-Mohammadzad

Abstract

Cardiac syndrome X (CSX) is a condition in which patients have the pain of angina despite normal coronary angiogram. Recently, Helicobacter pylori (H. pylori) bacteria has been associated with CSX. However, there is no obvious data about the frequency of its virulent strain (cytotoxine associated gene A: CagA) in patients with CSX. We surveyed the frequency of H. pylori and CagA antibodies in patients with cardiac syndrome X and healthy controls. Plasma samples from 100 CSX patients (61 females and 39 males; mean age: 51.8 ± 12.3 years) and 100 healthy controls (61 females and 39 males; mean age: 48.9 ± 6.3 years) were tested for the presence of IgG antibody to H. pylori using enzyme linked immunosorbent assay (ELISA) method. Also, infected patients were determined by the presence of IgG antibody to CagA by ELISA method. Statistical analysis was carried out using chi-square test and independent samples T-test. Ninety two percent (92/100) of patients were anti-H. pylori positive (anti-H. pylori+), while only 56.0% (56/100) of control group were anti-H. pylori+ (P<0.01). However, prevalence of anti-CagA positive (anti- CagA+) in H. pylori infected- CSX patients and control groups were 59.8% (55/92) and 60.7% (34/56), respectively...Continue Reading

References

Jan 1, 1993·Scandinavian Journal of Immunology·J E CrabtreeI J Lindley
Jan 5, 2000·Journal of Clinical Microbiology·S KatoM J Blaser
Jan 9, 2001·Southern Medical Journal·R NocenteA Gasbarrini
Mar 5, 2002·Clinical and Diagnostic Laboratory Immunology·Claudia Stöllberger, Josef Finsterer
May 1, 2002·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Andrew W Stadnyk
Sep 24, 2002·International Journal of Cardiology·G D GiannoglouG E Louridas
Nov 14, 2003·European Heart Journal·Ramón Arroyo-EspligueroJuan Carlos Kaski
Jun 29, 2004·The American Journal of Cardiology·Gaetano Antonio LanzaFilippo Crea
Sep 27, 2005·Medical Hypotheses·Jian-Jun LiHai-Yan Qian
Apr 12, 2006·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Ratko TomasevićAleksandar Pavlović
Jul 11, 2006·The American Journal of Medicine·Todd HurstChristopher P Appleton
Jan 24, 2007·Medical Hypotheses·Mehmet KanbayAli Akcay
Apr 7, 2007·Medical Hypotheses·Omer Faruk KaratasDogan Unal
Jun 26, 2007·World Journal of Gastroenterology : WJG·A JafarzadehM Nemati

❮ Previous
Next ❯

Citations

May 13, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Jacek BudzyńskiJacek Kubica
Jul 4, 2021·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Mohamed Riad

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay
ELISA

Software Mentioned

Statistical Package for Social Sciences ( SPSS )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.