PMID: 24353570Dec 20, 2013Paper

Frequency of migraine in patients with allergic rhinitis

Pakistan Journal of Medical Sciences
Ayhan OzturkAbdurrahman Tokmak

Abstract

Allergic rhinitis (AR) is an IgE mediated disease which is released by activation of mast cells and basophils, and often leads to sinus headache. Histamine which is the key mediator in the pathogenesis of AR, also plays an important role in the pathogenesis of migraine with nitric oxide (NO). Aim of our study was to investigate the frequency of migraine in patients with AR. Headache assessment and neurological examination was performed on patients diagnosed as AR in the outpatient ear nose and throat clinic with age-matched controls. Participants with headache were classified according to the International Headache Society criteria, and migraine frequency was investigated in the patients with AR and control groups. Migraine headache was detected in 50% of the patients with AR. Among these, 95% were migraine without aura, and 5% were migraine with aura. Migraine frequency in the control group was 18.75% in the control group, and all was migraine without aura. Migraine frequency in the patients with AR was four times higher when compared with the control group. While a histamine and IgE associated common mechanism is responsible in the pathogenesis of AR and migraine, not only sinus headache but also migraine headache should be k...Continue Reading

Citations

Mar 29, 2016·Seminars in Pediatric Neurology·Howard JacobsJack Gladstein
Oct 9, 2015·International Forum of Allergy & Rhinology·I-Chung WangChang-Ching Wei
May 6, 2015·European Journal of Pharmacology·Theoharis C TheoharidesIsaac Melamed
Feb 24, 2016·Current Neurology and Neuroscience Reports·Anna Gryglas
Mar 15, 2020·International Journal of Molecular Sciences·Dominique Belpomme, Philippe Irigaray

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