Frequency of P2RX7 A1513C and TLR2 -196 to -174 ins/del in healthy Polish individuals

International Journal of Immunogenetics
M LewandowskaH Witas

Abstract

Polymorphisms within genes coding innate immune response proteins are involved in genetic susceptibility to various conditions. We investigated the frequency of P2RX7 A1513C and TLR2 -196 to -174 ins/del polymorphisms in healthy Polish population. Frequency of minor alleles was relatively similar to the pattern presented by Caucasian populations while it differed significantly when compared to non-European populations, which could be a result of variable selection pressure put upon studied alleles or hindered gene flow between populations.

References

Aug 30, 2001·Proceedings of the National Academy of Sciences of the United States of America·R S WellsW F Bodmer
Oct 31, 2002·The Journal of Infectious Diseases·Cheuk M LiDavid A Lammas
Sep 19, 2003·American Journal of Human Genetics·Doron M BeharMichael E Weale
Nov 11, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Bernadette M SaundersJames S Wiley
Feb 28, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E NoguchiT Arinami
Nov 11, 2006·American Journal of Respiratory and Critical Care Medicine·Suran L FernandoWarwick J Britton
May 12, 2007·Clinical and Experimental Immunology·P Niño-MorenoR González-Amaro
Jun 15, 2007·Journal of Gastroenterology and Hepatology·Fangyu WangHiroshi Nakano
Apr 26, 2008·Journal of Medical Microbiology·Igor MokrousovOlga Narvskaya
Jul 11, 2008·Schizophrenia Research·Thomas HansenThomas Werge
Dec 17, 2008·FEMS Immunology and Medical Microbiology·Jing XiaoAdong Shen
May 25, 2010·Liver International : Official Journal of the International Association for the Study of the Liver·Kshitij SrivastavaBalraj Mittal
Jul 28, 2010·The Pediatric Infectious Disease Journal·Deniz TekinBetul Aydin Kilic
Jan 29, 2011·The Lancet Infectious Diseases·Emilie AlirolLouis Loutan
Feb 10, 2011·Recent Patents on DNA & Gene Sequences·Ronald Sluyter, Leanne Stokes
Apr 19, 2011·International Journal of Cancer. Journal International Du Cancer·Hans-Dieter NischalkeUlrich Spengler
Oct 13, 2011·Tissue Antigens·J S WileyS J Fuller
Apr 3, 2012·World Journal of Gastroenterology : WJG·Juliana Garcia de Oliveira, Ana Elizabete Silva
May 4, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Kallirhoe KalinderiLiana Fidani
May 9, 2012·The Breast : Official Journal of the European Society of Mastology·George E TheodoropoulosGeorge C Zografos
Jun 19, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L B HustedB L Langdahl
Mar 22, 2014·Biomedical Reports·Yan CaiJing-Guo Zhou
Jun 3, 2014·Journal of Affective Disorders·José OliveiraRyad Tamouza

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