Frequency of the C282Y mutation of hemochromatosis in five French populations

Blood Cells, Molecules & Diseases
G MercierGérard Lucotte

Abstract

Hereditary hemochromatosis mutation 845A (C282Y) in the HFE gene was recently described, and the C282Y frequencies were reported for various world populations. The aim of this study was to determine the Y allele frequencies of the C282Y mutation for five French populations. The most elevated value (= 5.6%) was obtained for Bretons, in accordance to the hypothesis indicating a Celtic origin of the hereditary hemochromatosis mutation.

Citations

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Dec 16, 1998·Blood Cells, Molecules & Diseases·G Lucotte
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