Frequency-Swept Integrated and Stretched Solid Effect Dynamic Nuclear Polarization.

The Journal of Physical Chemistry Letters
T V CanRobert G Griffin

Abstract

We investigate a new time domain approach to dynamic nuclear polarization (DNP), the frequency-swept integrated solid effect (FS-ISE), utilizing a high power, broadband 94 GHz (3.35 T) pulse EPR spectrometer. The bandwidth of the spectrometer enabled measurement of the DNP Zeeman frequency/field profile that revealed two dominant polarization mechanisms, the expected ISE, and a recently observed mechanism, the stretched solid effect (S2E). At 94 GHz, despite the limitations in the microwave chirp pulse length (10 μs) and the repetition rate (2 kHz), we obtained signal enhancements up to ∼70 for the S2E and ∼50 for the ISE. The results successfully demonstrate the viability of the FS-ISE and S2E DNP at a frequency 10 times higher than previous studies. Our results also suggest that these approaches are candidates for implementation at higher magnetic fields.

References

Jan 16, 2008·Proceedings of the National Academy of Sciences of the United States of America·Melody L Mak-JurkauskasJudith Herzfeld
May 29, 2009·Proceedings of the National Academy of Sciences of the United States of America·Vikram S BajajRobert G Griffin
Apr 30, 2010·Physical Chemistry Chemical Physics : PCCP·Robert I HunterGraham M Smith
Sep 14, 2010·Journal of the American Chemical Society·Anne LesageLyndon Emsley
Nov 19, 2010·Journal of Magnetic Resonance·Yonatan HovavShimon Vega
Aug 17, 2012·The Journal of Chemical Physics·Björn CorziliusRobert G Griffin
Sep 13, 2012·Journal of the American Chemical Society·Aaron J RossiniLyndon Emsley
Sep 15, 2012·Journal of Magnetic Resonance·Albert A SmithRobert G Griffin
May 22, 2013·Journal of Biomolecular NMR·Ioannis GelisGeoffrey Bodenhausen
Nov 28, 2013·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Pascal FrickeAdam Lange
Dec 18, 2013·Journal of Magnetic Resonance·Y HovavD Goldfarb
Aug 20, 2014·The Journal of Chemical Physics·T V CanR G Griffin
Jul 29, 2015·Proceedings of the National Academy of Sciences of the United States of America·Johanna Becker-BaldusClemens Glaubitz
Aug 2, 2015·Journal of Magnetic Resonance·Frederic Mentink-VigierAkiva Feintuch
Aug 10, 2015·The Journal of Chemical Physics·T V CanR G Griffin
Sep 1, 2015·Chemistry : a European Journal·Elwin A W van der CruijsenMarc Baldus
Nov 3, 2015·Journal of Magnetic Resonance·Mallory L GuyChandrasekhar Ramanathan
Dec 15, 2015·The Journal of Physical Chemistry Letters·Guinevere MathiesRobert G Griffin
Apr 21, 2016·Journal of Magnetic Resonance·Ümit Akbey, Hartmut Oschkinat
Jun 29, 2016·Journal of Biomolecular NMR·Pascal FrickeAdam Lange
Aug 24, 2016·Science Advances·Sascha LangeHartmut Oschkinat
Apr 24, 2017·The Journal of Chemical Physics·T V CanR G Griffin
May 10, 2017·Journal of Magnetic Resonance·Ilia KaminkerSongi Han
May 13, 2017·Angewandte Chemie·Thach V CanRobert G Griffin
Jun 6, 2017·Journal of Magnetic Resonance·Philipp E SpindlerThomas F Prisner
Nov 4, 2017·The Journal of Chemical Physics·Sheetal K JainRobert G Griffin
Nov 10, 2017·Journal of Biomolecular NMR·Thomas WiegandBeat H Meier
Nov 22, 2017·Progress in Nuclear Magnetic Resonance Spectroscopy·Aany Sofia Lilly ThankamonyBjörn Corzilius

❮ Previous
Next ❯

Citations

Feb 20, 2020·Annual Review of Physical Chemistry·Björn Corzilius
Oct 31, 2018·Physical Chemistry Chemical Physics : PCCP·Alisa LeavesleySongi Han
Feb 13, 2019·Science Advances·Kong Ooi TanRobert G Griffin
Jul 23, 2019·Journal of Magnetic Resonance·Robert G GriffinRichard J Temkin
Jan 12, 2021·Journal of Magnetic Resonance·Bulat GizatullinSiegfried Stapf
Apr 7, 2019·Journal of Magnetic Resonance·Armin PureaFrank Engelke
Mar 6, 2019·Solid State Nuclear Magnetic Resonance·Pierre ThureauGiulia Mollica
Jun 13, 2019·Solid State Nuclear Magnetic Resonance·Andrew G M RankinOlivier Lafon
Jun 30, 2021·Journal of Magnetic Resonance·T V CanR G Griffin
Apr 14, 2020·The Journal of Physical Chemistry Letters·Kong Ooi TanRobert G Griffin
Jul 28, 2019·The Journal of Physical Chemistry Letters·Scott L CarnahanAaron J Rossini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Angewandte Chemie
Thach V CanRobert G Griffin
Physical Chemistry Chemical Physics : PCCP
Robert I HunterGraham M Smith
Physical Chemistry Chemical Physics : PCCP
Vasyl P DenysenkovThomas F Prisner
Journal of the American Chemical Society
M J PrandoliniThomas F Prisner
© 2022 Meta ULC. All rights reserved