Frequency-Swept Integrated Solid Effect

Angewandte Chemie
Thach V CanR G Griffin

Abstract

The efficiency of continuous wave dynamic nuclear polarization (DNP) experiments decreases at the high magnetic fields used in contemporary high-resolution NMR applications. To recover the expected signal enhancements from DNP, we explored time domain experiments such as NOVEL which matches the electron Rabi frequency to the nuclear Larmor frequency to mediate polarization transfer. However, satisfying this matching condition at high frequencies is technically demanding. As an alternative we report here frequency-swept integrated solid effect (FS-ISE) experiments that allow low power sweeps of the exciting microwave frequencies to constructively integrate the negative and positive polarizations of the solid effect, thereby producing a polarization efficiency comparable to (±10 % difference) NOVEL. Finally, the microwave frequency modulation results in field profiles that exhibit new features that we coin the "stretched" solid effect.

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Citations

Dec 2, 2017·Magnetic Resonance in Chemistry : MRC·Li ZhaoAaron J Rossini
Jul 10, 2019·Physical Chemistry Chemical Physics : PCCP·Koki NishimuraNobuhiro Yanai
Feb 13, 2019·Science Advances·Kong Ooi TanRobert G Griffin
Nov 4, 2017·The Journal of Chemical Physics·Sheetal K JainRobert G Griffin
Feb 20, 2020·Annual Review of Physical Chemistry·Björn Corzilius
Oct 4, 2018·Proceedings of the National Academy of Sciences of the United States of America·A AjoyA Pines
Jul 31, 2019·Science Advances·Kong Ooi TanRobert G Griffin
Sep 27, 2018·Science Advances·Pinhui ChenAlexander B Barnes
Jul 23, 2019·Journal of Magnetic Resonance·Robert G GriffinRichard J Temkin
Aug 5, 2018·Journal of Magnetic Resonance·Erika L SestiAlexander B Barnes
Feb 23, 2018·Journal of Magnetic Resonance·Faith J ScottAlexander B Barnes
Apr 7, 2019·Journal of Magnetic Resonance·Armin PureaFrank Engelke
Apr 13, 2019·Journal of Magnetic Resonance·Chukun GaoAlexander B Barnes
Jun 13, 2019·Solid State Nuclear Magnetic Resonance·Andrew G M RankinOlivier Lafon
Jun 30, 2021·Journal of Magnetic Resonance·T V CanR G Griffin
Aug 15, 2018·The Journal of Physical Chemistry Letters·Aaron J Rossini
May 15, 2018·The Journal of Physical Chemistry Letters·T V CanR G Griffin
Sep 6, 2018·The Journal of Physical Chemistry Letters·Edward P SalibaAlexander B Barnes
Aug 22, 2018·Journal of the American Chemical Society·Pan WangTimothy M Swager
Apr 14, 2020·The Journal of Physical Chemistry Letters·Kong Ooi TanRobert G Griffin
Jan 1, 2022·Proceedings of the National Academy of Sciences of the United States of America·Salima BahriRobert G Griffin

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