Frequent unifocal ventricular premature contractions that caused dilated cardiomyopathy: resolution of myocardial function after successful catheter-ablation of arrhythmia focus

Srpski arhiv za celokupno lekarstvo
Nebojša MujovićNataša Mujović

Abstract

In patients with dilated cardiomyopathy (DCM) and frequent ventricular premature beats (VPBs) it may be difficult to evaluate whether ventricular arrhythmia is the cause or consequence of heart failure. However, it is very important to recognize VPBs as a potentially reversible cause of myocardial dysfunction, because arrhythmia suppression in these patients may lead to recovery of myocardial contractility. An asymptomatic 24-year-old man with DCM and frequent VPBs of left bundle branch morphology with inferior axis was referred to our Department for further evaluation. Echocardiographic examination showed left ventricular dilation with reduced ejection fraction to 40%, while 24 h Holter-monitoring recorded 31,000 isolated VPBs refractory to drug treatment. During the electrophysiologic study a VPBs' focus in the right ventricular outflow tract was identified which was successfully resolved by radiofrequency catheter-ablation. Immediately after the procedure, considerable suppression of VES number to 2500/24 h was confirmed by Holter-recording, while complete recovery of left ventricular function was detected one month later by echocardiographic re-examination. Recognition of causal-resultant relation between frequent VPBs and ...Continue Reading

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Y BlaauwH J G M Crijns
Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Mirja A PeltolaCardiac Arrhythmias and Risk Stratification after Acute Myocardial Infarction (CARISMA) Investigators
© 2022 Meta ULC. All rights reserved