Fresh Frozen Plasma and Platelet Transfusion Practices in Neonatal Intensive Care Unit of a Tertiary Care Hospital

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
Kanchan DograDeepak Chawla

Abstract

Blood transfusion is an indispensable part of modern medical and surgical practices. More than 35% of critically ill patients receive transfusion of blood components during their intensive care unit stay. The aim of study is to obtain an information regarding the relationship of platelet concentrate (PC) and fresh frozen plasma (FFP) transfusion on clinical outcome of neonates admitted in neonatal ICU (NICU). This prospective cohort study was conducted from 1st November 2011 to 30th April 2013. The clinical history, blood component details and laboratory parameters were evaluated with clinical outcome. The neonates requiring PC and FFP transfusion were followed up in blood bank for laboratory parameters. Clinical parameters were noted from case file. During the study period, 291 neonates were admitted in NICU. 2 neonates had congenital malformations and thus, were excluded from the study. Of the remaining 289 neonates, 49 neonates received transfusion of platelets and/or FFP. The combined mean donor exposure for all components was found to be 1.48. The mean volume of PC and FFP transfused was 20 ml and 30 ml respectively. The mean pre- and post-transfusion platelet count was 34,000 µl and 42,000 µl respectively. The mean pre- a...Continue Reading

References

Sep 24, 2002·JAMA : the Journal of the American Medical Association·Jean Louis VincentUNKNOWN ABC (Anemia and Blood Transfusion in Critical Care) Investigators
Dec 4, 2004·Journal of Perinatology : Official Journal of the California Perinatal Association·Alexander B KentonCaraciolo J Fernandes
Oct 21, 2009·Pediatrics·Simon J StanworthUNKNOWN Platelets and Neonatal Transfusion Study Group
Feb 15, 2011·BMC Pediatrics·Jeannette S von LindernFrans J Walther
May 30, 2012·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Nilgün AltuntasYıldız Atalay
Mar 22, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·Mario MottaMaurizio Radicioni
Oct 11, 2014·Neonatology·Robert CarrLorna M Williamson
May 24, 2016·JAMA Pediatrics·Katherine A SpargerMartha Sola-Visner

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