PMID: 11912052Mar 26, 2002Paper

Freshwater pollution biomarker: response of brain acetylcholinesterase activity in two fish species

Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP
F R de la TorreA Salibián

Abstract

The effect of prolonged exposure at two sites along the Reconquista River (Argentina), a highly polluted peri-urban water body, on brain acetylcholinesterase (AChE, EC 3.1.1.7, acetylcholine acetylhydrolase) of two teleosts was examined. Caged Cyprinus carpio and field-captured Cnesterodon decemmaculatus were used as sentinel organisms. Eserine concentration inhibiting 50% of AChE activity (IC50) and inhibition kinetic parameters were also evaluated. Interspecies IC50 differences were found to agree with observed kinetic parameters (KA, ki and kc), indicating that carps were more sensitive to eserine. Data obtained disclosed spatial differences and demonstrated the high sensitivity of AChE activity as an exposure biomarker. Marked species-related differences were detected, showing that enzyme determination of C. decemmaculatus is more effective in highly polluted sites. Considering the river water physicochemical profile, observed changes in AChE activities can be partly attributed to long-lasting raised concentrations of dissolved heavy metals.

References

Jan 1, 1986·Residue Reviews·T M Smith, G W Stratton
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·C HabigM B Abou-Donia
Apr 1, 1987·Toxicology and Applied Pharmacology·J A Johnson, K B Wallace
Apr 1, 1997·Bulletin of Environmental Contamination and Toxicology·F R de la TorreA Salibián
Mar 4, 1998·Bulletin of Environmental Contamination and Toxicology·V L BastosJ C Bastos
Sep 11, 1998·Archives of Environmental Contamination and Toxicology·S J Gruber, M D Munn
Nov 25, 1998·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·J M Monserrat, A Bianchini
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE
Apr 20, 2004·Environmental Pollution·F R de la TorreL Ferrari
Apr 1, 1995·Environmental Monitoring and Assessment·T SzegletesJ Nemcsók

❮ Previous
Next ❯

Citations

Jun 6, 2007·Archives of Environmental Contamination and Toxicology·J Venkateswara RaoP K Usman
Dec 1, 2009·Archives of Environmental Contamination and Toxicology·Alexandra PrettoValderi Dressler
Nov 6, 2012·Archives of Environmental Contamination and Toxicology·Andrea Cecilia HuedMaría de Los Ángeles Bistoni
Aug 10, 2013·Archives of Environmental Contamination and Toxicology·Fabiane G AntesValderi L Dressler
Sep 4, 2009·Environmental Monitoring and Assessment·Sofiene TliliHamadi Boussetta
Nov 11, 2009·Biological Trace Element Research·Abdel-Hasseb A Fayed
Dec 4, 2003·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·L IntorreC Pretti
Apr 5, 2014·International Journal of Environmental Research and Public Health·Yi HuangTinglin Huang
Aug 19, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Sonali RoyShelley Bhattacharya
Feb 8, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·M Q YiX W Gao
Dec 3, 2014·Ecotoxicology and Environmental Safety·Renata J Menéndez-HelmanAlfredo Salibián
Jul 11, 2006·Environmental Research·Denise FernandesMaria João Bebianno
Apr 22, 2014·The Science of the Total Environment·Isa D L GomesMelissa Faria
Aug 4, 2012·Marine Pollution Bulletin·Milagrosa OlivaMaría Dolores Galindo-Riaño
Oct 15, 2013·Marine Pollution Bulletin·Fátima BrandãoBruno Nunes
Jan 7, 2015·Metallomics : Integrated Biometal Science·Rita M GodinhoTeresa Pinheiro
Jul 1, 2006·Environmental Toxicology and Pharmacology·Ilhan AltinokMuhammet Boran
Apr 1, 2020·Histochemistry and Cell Biology·Sherif Mohamed ZakiFatma M Ghoneim
Oct 19, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·José M MonserratAdalto Bianchini
Sep 6, 2020·The Science of the Total Environment·Douglas Dos Santos SilvaThiago Lopes Rocha

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.