Frey procedure in patients with chronic pancreatitis: short and long-term outcome from a prospective study.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Alexandra M D RochJean-Pierre Arnaud

Abstract

The aim of this prospective study was to determine the short- and long-term results of the Frey procedure in the treatment of chronic pancreatitis. From September 2000 to November 2009, 44 consecutive patients underwent the Frey procedure. Patients were included in the study before surgery and followed prospectively with assessment of pain relief, weight gain and exocrine/endocrine insufficiency. Twenty-one patients (47.7%) were followed for more than 5 years. This study included 40 men (91 %) and four women (9 %) (mean age: 49 years) with a mean follow-up of 51.5 months. The primary etiology of chronic pancreatitis was chronic alcohol abuse in 38 patients (86.4 %). The major indication for surgery was disabling pain (95.5 %). There was no postoperative mortality. Postoperative morbidity occurred in 15 patients (34.1 %), with specific surgical complications in 11 patients (25 %). The percentage of pain-free patients after surgery was 68.3 %. Eight patients (18.1 %) and seven patients (16 %) developed diabetes de novo and exocrine insufficiency, respectively. The Body Mass Index showed statistically significant improvement during follow-up. Similar beneficial results concerning pain relief and weight gain persisted after the ini...Continue Reading

References

Sep 2, 1999·The Surgical Clinics of North America·J R IzbickiT Kuechler
May 19, 2000·Annals of Surgery·J J HuangJ L Cameron
Sep 28, 2002·European Journal of Gastroenterology & Hepatology·Ake Andrén-SandbergHjörtur Gislason
Apr 25, 2003·Langenbeck's Archives of Surgery·Mark HartelMarkus W Büchler
Jun 1, 1958·A.M.A. Archives of Surgery·C B PUESTOW, W J GILLESBY
Dec 1, 1960·Annals of Surgery·P F PARTINGTON, R E ROCHELLE
Sep 29, 2004·American Journal of Surgery·Adarsh ChaudharyMahesh Thombare
Jul 9, 2005·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Fistula Definition
Sep 30, 2005·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Charles F Frey, Howard A Reber
Feb 4, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shailesh V ShrikhandeMarkus W Büchler
Apr 22, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Massimo FalconiPaolo Pederzoli
Nov 3, 2006·Pancreas·Patrick PessauxAlain Sauvanet
Dec 17, 2009·Annals of Surgery·Dana K Andersen, Charles F Frey
Dec 25, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Tobias KeckFrank Makowiec
Mar 15, 2011·Lancet·Joan M BraganzaMichael J McMahon
Jun 4, 2011·Clinical Oncology : a Journal of the Royal College of Radiologists·K Forbes
Oct 15, 2011·Journal of the American College of Surgeons·Chirag S DesaiRainer W G Gruessner

❮ Previous
Next ❯

Citations

Jan 18, 2013·World Journal of Gastroenterology : WJG·Beata Jabłońska
Nov 30, 2018·European Journal of Gastroenterology & Hepatology·Minas BaltatzisAjith K Siriwardena
Jan 7, 2017·World Journal of Gastroenterology : WJG·Chun-Lu TanKe-Zhou Li
Sep 20, 2019·BMC Surgery·Dhruba Narayan SahPaleswan Joshi Lakhey
Oct 24, 2014·Journal of Hepato-biliary-pancreatic Sciences·Junji UedaMasao Tanaka
Oct 27, 2016·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·S MaheshH Ramesh
Jun 10, 2020·Pediatric Surgery International·Sukanta RaySujan Khamrui
Jul 11, 2020·Journal of Visceral Surgery·P TortajadaL Schwarz
Feb 21, 2021·American Journal of Surgery·Sukanta RayZuber Ansari
Feb 28, 2021·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Minas BaltatzisAjith K Siriwardena

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.