From basic research to public health policy: WHO report on the neuroscience of substance dependence

Addictive Behaviors
Isidore S ObotMaristela Monteiro

Abstract

The World Health Organization (WHO) report on the Neuroscience of Psychoactive Substance Use and Dependence represents a summary of the latest scientific knowledge on the role of the brain in substance dependence. The findings of the report have important applications to both interventions and public health policy. Specifically, the report notes that psychoactive substances have physical and symbolic effects that are rewarding to the user. It notes that adverse consequences of psychoactive substance use are related to the level, pattern, mode, and context of use. Dependence is seen as a complex disorder involving brain mechanisms rather than a failure of will. The report notes that psychoactive substance use often coexists with other mental health problems, and that stigma associated with substance misuse inhibits treatment seeking. There is growing evidence for the efficacy and effectiveness of interventions, including advances in pharmacotherapy. However, these advances raise ethical issues that need to be addressed.

References

Jul 1, 1992·Journal of Psychoactive Drugs·S Murphy, J Irwin
Nov 21, 1990·JAMA : the Journal of the American Medical Association·D A RegierF K Goodwin
Jul 1, 1997·The Journal of Neuropsychiatry and Clinical Neurosciences·G F Koob, E J Nestler

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Citations

Mar 5, 2016·Andrologia·N A KumsarN Dilbaz
Dec 13, 2005·Nature Reviews. Neuroscience·Judy IllesPiergiorgio Strata
Aug 20, 2009·Nursing & Health Sciences·Ladda SanseehaSue Turale
Apr 24, 2015·The Journal of Headache and Pain·Isabel MorganMichelle A Williams
Sep 11, 2010·Journal of the American Society of Nephrology : JASN·Stephen P GrayKaren M Moritz
Dec 16, 2005·Cell Research·Bei Chuan Zhang, Quan Sheng Chu
Nov 30, 2006·Drug and Alcohol Review·Ben Baumberg
Apr 30, 2009·Annual Review of Plant Biology·Peggy G Lemaux
Sep 25, 2010·American Journal of Public Health·Reece HinchcliffTeresa Senserrick
Sep 1, 2011·SAHARA J : Journal of Social Aspects of HIV/AIDS Research Alliance·Pranitha Maharaj, John Cleland

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