From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products

Frontiers in Genetics
Amanat AliRanjit Vijayan

Abstract

Camels have an important role in the lives of human beings, especially in arid regions, due to their multipurpose role and unique ability to adapt to harsh conditions. In spite of its enormous economic, cultural, and biological importance, the camel genome has not been widely studied. The size of camel genome is roughly 2.38 GB, containing over 20,000 genes. The unusual genetic makeup of the camel is the main reason behind its ability to survive under extreme environmental conditions. The camel genome harbors several unique variations which are being investigated for the treatment of several disorders. Various natural products from camels have also been tested and prescribed as adjunct therapy to control the progression of ailments. Interestingly, the camel employs unique immunological and molecular mechanisms against pathogenic agents and pathological conditions. Here, we broadly review camel classification, distribution and breed as well as recent progress in the determination of the camel genome, its size, genetic distribution, response to various physiological conditions, immunogenetics and the medicinal potential of camel gene products.

References

Jun 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J P FinbergG M Berlyne
Jan 1, 1985·Annual Review of Immunology·J A TainerR A Lerner
Jan 1, 1988·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·A K Al-AliD M Power
Mar 11, 1981·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·K Schmidt-NielsenH T Hammel
Jan 1, 1983·Comparative Biochemistry and Physiology. A, Comparative Physiology·H M MousaI D Hume
Mar 1, 1980·JPEN. Journal of Parenteral and Enteral Nutrition·B AnderssonM Rundgren
Dec 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·H A UlmasovM B Evgen'ev
Jun 3, 1993·Nature·C Hamers-CastermanR Hamers
Oct 1, 1996·The American Journal of Physiology·M A CarrollJ C McGiff
Aug 1, 1997·Journal of Virology·M YiS Murakami
Sep 1, 1997·Comparative Biochemistry and Physiology. Part A, Physiology·B ElmahdiM Kaske
May 9, 1998·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·M MarchettiN Orsi
May 8, 1998·Biochemical and Biophysical Research Communications·M IkedaN Kato
Jul 9, 1999·Journal of Molecular Recognition : JMR·S Muyldermans, M Lauwereys
Apr 14, 2000·Journal of Animal Science·I OlesenB Gjerde
Apr 28, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·I C West
Aug 19, 2000·The Veterinary Journal·N D BeuzenK C Chang
Oct 13, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·S Nagai, M Toi
Feb 13, 2001·Biophysical Journal·T H Thanka Christlet, K Veluraja
Mar 10, 2001·Nature·E S LanderUNKNOWN International Human Genome Sequencing Consortium
Apr 9, 2001·American Journal of Physiology. Renal Physiology·Y HuangA N Van Hoek
Aug 31, 2001·Journal of Biotechnology·S Muyldermans
Nov 1, 2001·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·M KaskeH P Sallmann
Mar 29, 2002·International Journal of Cancer. Journal International Du Cancer·Virna Cortez-RetamozoHilde Revets
Jul 13, 2002·International Journal of Cancer. Journal International Du Cancer·Yukinobu MaruoKunzo Orita
Dec 6, 2002·Nature·UNKNOWN Mouse Genome Sequencing ConsortiumEric S Lander
Jun 6, 2003·Nature·Jared Diamond
Aug 15, 2003·Nature·Mireille DumoulinChristopher M Dobson
Sep 11, 2003·The Lancet Oncology·Peter W Szlosarek, Frances R Balkwill
Jan 1, 1957·The American Journal of Physiology·K SCHMIDT-NIELSENT R HOUPT
Feb 6, 2004·Toxicon : Official Journal of the International Society on Toxinology·Fatma Meddeb-MouelhiMohamed El Ayeb
Feb 19, 2004·Nature Reviews. Genetics·Leif Andersson, Michel Georges
Aug 11, 2004·The Veterinary Journal·U Wernery, O-R Kaaden

❮ Previous
Next ❯

Citations

Oct 15, 2019·Frontiers in Genetics·Hussain BahbahaniOlivier Hanotte
Nov 5, 2019·Frontiers in Genetics·Salvatrice CiccareseRachele Antonacci
Dec 6, 2020·International Journal of Biological Macromolecules·Ajamaluddin MalikMohammad Z Ahmed
Feb 12, 2021·Frontiers in Immunology·Jamal Hussen, Hans-Joachim Schuberth
Jan 12, 2021·Saudi Journal of Biological Sciences·Doaa KiratTaku Miyasho
Mar 7, 2021·Animals : an Open Access Journal From MDPI·Martina ZappaterraBarbara Padalino
May 8, 2020·International Journal of Biological Macromolecules·Ejlal Mohamed AbdullahAjamaluddin Malik
Mar 20, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Sirajudheen AnwarKannan Rr Rengasamy
Apr 4, 2021·Animals : an Open Access Journal From MDPI·El Tigani Ahmed El Tigani-AsilSalama Suhail Al Muhairi
Apr 18, 2021·Trends in Ecology & Evolution·Joana L RochaRasmus Nielsen

❮ Previous
Next ❯

Methods Mentioned

BETA
two hybrid
glycosylation
electrophoresis
PCR
bioluminescence resonance

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Related Papers

Nordisk medicin
H T Andersen
Verhandlungen der Deutschen Gesellschaft für Innere Medizin
G Riethmüller
Interdisciplinary Sciences, Computational Life Sciences
Amar RanjanDev Mani Pandey
© 2021 Meta ULC. All rights reserved