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From genome to function by studying eQTLs

Biochimica Et Biophysica Acta

May 7, 2014

Harm-Jan Westra, Lude Franke

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PubMed

Abstract

Genome-wide association studies (GWASs) have shown a large number of genetic variants to be associated with complex diseases. The identification of the causal variant within an associated locus can sometimes be difficult because of the linkage disequilibrium between the associated varia...read more

Mentioned in this Paper

Genome-Wide Association Study
Diabetes Mellitus, Non-Insulin-Dependent
Pathogenic Aspects
Biochemical Pathway
Quantitative Trait Loci
T-Lymphocyte
Meta-Analysis (Publications)
Deoxyribonuclease I
Pathogenesis
Specimen Type - Fibroblasts
1
284
Paper Details
References
  • References66
  • Citations40
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  • References66
  • Citations40
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From genome to function by studying eQTLs

Biochimica Et Biophysica Acta

May 7, 2014

Harm-Jan Westra, Lude Franke

PMID: 24798236

DOI: 10.1016/j.bbadis.2014.04.024

Abstract

Genome-wide association studies (GWASs) have shown a large number of genetic variants to be associated with complex diseases. The identification of the causal variant within an associated locus can sometimes be difficult because of the linkage disequilibrium between the associated varia...read more

Mentioned in this Paper

Genome-Wide Association Study
Diabetes Mellitus, Non-Insulin-Dependent
Pathogenic Aspects
Biochemical Pathway
Quantitative Trait Loci
T-Lymphocyte
Meta-Analysis (Publications)
Deoxyribonuclease I
Pathogenesis
Specimen Type - Fibroblasts
1
284

Feeds With Similar Papers

RNA Splicing (Keystone)

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

Influenza

Influenza, commonly known as the flu, is an infectious disease caused by an influenza virus.Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and feeling tired. Discover the latest research on influenza here.

Related Papers

Frontiers in Genetics

A review of post-GWAS prioritization approaches

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Paper Details
References
  • References66
  • Citations40
12345...
  • References66
  • Citations40
1234

Download from

Publisher
PubMed
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