The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA splicing and co-transcriptional splicing in this feed.

Influenza, commonly known as the flu, is an infectious disease caused by an influenza virus.Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and feeling tired. Discover the latest research on influenza here.

Epigenetics is the study of heritable changes in gene expression that do not involve alteration of the DNA sequence. Here is the latest research.

Exon skipping is a method of RNA splicing used when a mutation occurs in the genes of exons. It is regulated largely by the use of antisense oligonucleotides that mask the mutated gene and allow the cellular machinery to skip over it. Exon skipping is being investigated as a therapeutic option for some diseases. Here is the latest research on exon skipping.

While type 2 diabetes (T2D) is heritable, less than 20% of this heritability is explained by known genetic variants. This discrepancy maybe explained by epigenetic changes and epigenetic inheritance in pancreatic cells. Here is the latest research on the epigenetic control of beta cell function and failure in T2D.

Emerging Infectious Diseases are defined as those whose incidence in humans has increased in the past two decades or threaten to increase in the near future. Discover the latest research on Emerging Infectious Diseases.

Viral respiratory infections can affect the upper or lower respiratory tract. These lung and airway infections can be caused by numerous different viruses and can be dangerous for those who have a weakened immune system. Discover the latest research on viral respiratory diseases here.

B lymphocytes are white blood cells that play a role in the adaptive immune system by secreting antibodies. Here is the latest research on gene expression in B cells.

The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. Discover the latest research on RNA Splicing here.

This feed focuses on Type 2 Diabetes, a disease where the body doesn’t produce or respond to insulin anymore, leading to abnormal glucose levels in the blood.

Influenza, commonly known as the flu, is an infectious disease caused by an influenza virus.Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle pains, headache, coughing, sneezing, and feeling tired. Discover the latest research on influenza here.

Expression Quantitative Trait Loci (eQTL) analysis is the identification of specific or groups of genetic variants that affect gene expression levels within the cell. Discover the latest research on Expression Quantitative Trait Loci Analysis here.

Epigenetics is the study of heritable changes in gene expression that do not involve alteration of the DNA sequence. Here is the latest research.

Via interaction with their specific receptors, interferons (IFNs) activate signal transducer and activator of transcription (STAT) complexes. STAT activation initiates the classical Janus kinase-STAT (JAK-STAT) signaling pathway. In this pathway, JAKs associate with IFN receptors and, following receptor engagement with IFN, phosphorylate both STAT1 and STAT2. As a result, an IFN-stimulated gene factor 3 (ISGF3) complex forms—this contains STAT1, STAT2 and a third transcription factor called IRF9—and moves into the cell nucleus. Inside the nucleus, the ISGF3 complex binds to specific nucleotide sequences called IFN-stimulated response elements (ISREs) in the promoters of certain genes, known as IFN stimulated genes. Discover the latest research on interferon signalling here.

Influenza viruses comprise a major class of human respiratory pathogens, responsible for causing morbidity and mortality worldwide. Discover the latest research on Influenza Viruses here.

Genetic epidemiology examines the role of genetic factors in determining health and disease in populations and the interaction between these genetic factors with environmental factors. Here is the latest research on the genetic epidemiology of complex multifactorial diseases like cancer.