From Mice to Men: TRPC3 in Cerebellar Ataxia

The Cerebellum
Esther B E Becker

Abstract

The dominantly inherited cerebellar ataxias are a clinically and genetically heterogeneous group of neurodegenerative disorders. Studies using mouse models as well as recent genetic and transcriptomic human findings point to an important role for TRPC3 signaling in cerebellar ataxia.

References

Apr 9, 2009·Proceedings of the National Academy of Sciences of the United States of America·Esther B E BeckerKay E Davies
Dec 25, 2009·Current Molecular Pharmacology·F Metzger
Feb 15, 2013·The Cerebellum·Sang Jeong Kim
Sep 14, 2013·Brain : a Journal of Neurology·Andrea H NémethJiannis Ragoussis
May 21, 2014·ELife·Haibo ZhouMartijn Schonewille
May 28, 2014·JAMA Neurology·Conceição BettencourtUNKNOWN United Kingdom Brain Expression Consortium
Dec 6, 2014·Movement Disorders : Official Journal of the Movement Disorder Society·Brent L FogelEsther B E Becker

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Citations

Jan 2, 2020·International Journal of Molecular Sciences·Francesca PrestoriEgidio D'Angelo
Sep 27, 2018·Acta Neuropathologica Communications·Maggie M K WongEsther B E Becker
Aug 9, 2020·Frontiers in Neuroscience·Katherine J RobinsonAngela S Laird
Sep 17, 2020·International Journal of Molecular Sciences·Aleksandar ArsovićGeorg Auburger
Nov 27, 2020·Frontiers in Cell and Developmental Biology·Boris LavanderosOscar Cerda

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Methods Mentioned

BETA
laser capture microdissection
exome sequencing

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