From oral facial dysfunction to dysmorphism and the onset of pediatric OSA

Sleep Medicine Reviews
Christian Guilleminault, Yu-Shu Huang

Abstract

The upper airway is a collapsible tube, and its collapsibility increases during sleep. Extrinsic factors such as atypical craniofacial features may increase the risks of airway collapse. We review early development of oral-facial structures and the anatomical variants that may be present at birth and can impact nasal breathing. After birth, there is a continuous interaction between orofacial functions and growth of anatomic features. We review the dysfunctions identified to date that may impact orofacial development leading to sleep-disordered-breathing through changes in the orofacial growth. The identification of risk-factors, ultimately leading to full-blown obstructive sleep apnea, may allow early recognition of these factors and the development of treatments to eliminate early problems or at least decrease their impact.

Citations

Jan 29, 2019·Expert Review of Respiratory Medicine·William C Arnold, Christian Guilleminault
Oct 28, 2019·Journal of Clinical Medicine·Olga MedianoFrancisco García-Río
Oct 4, 2019·Sleep·Christian GuilleminaultStacey Quo
Apr 9, 2020·Journal of Clinical Medicine·Yu-Shu HuangHsueh-Yu Li
Feb 26, 2020·Sleep·Pablo E BrockmannDavid Gozal
Dec 25, 2019·Sleep Medicine·Maria Pia VillaAthanasios Kaditis
Mar 11, 2021·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Eric ThulerSergio Samir Arap
Jul 3, 2021·International Journal of Environmental Research and Public Health·Miriam FioravantiGian Luca Sfasciotti

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