Abstract
The application of aspirin-like drugs in modern medicine is very broad, encompassing the treatment of inflammation, pain and a variety of cardiovascular conditions. Although anecdotal accounts of willow bark extract as an anti-inflammatory drug have occurred since written records began (for example by Hippocrates), the first convincing demonstration of a potent anti-pyretic effect of willow bark containing salicylates was made by the English cleric Edward Stone in the late eighteenth century. Here, we discuss the route to optimizing and understanding the mechanism of action of anti-inflammatory drugs that have their origins in Stone's seminal study, 'An account of the success of the bark of the willow in the cure of agues'. This commentary was written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society.
References
Oct 1, 1992·Stroke; a Journal of Cerebral Circulation·H TohgiK Kawano
Feb 1, 1990·Controlled Clinical Trials·W A Silverman
Mar 28, 1971·Nature·J H Burn
Jun 23, 1971·Nature: New Biology·S H FerreiraJ R Vane
Dec 19, 1996·Nature·R G KurumbailW C Stallings
Jun 23, 2000·Journal of the American Academy of Dermatology·M R Heaphy, A B Ackerman
Dec 22, 2000·BMJ : British Medical Journal·W Sneader
Aug 31, 2001·JAMA : the Journal of the American Medical Association·D MukherjeeE J Topol
Jul 1, 1997·Notes and Records of the Royal Society of London·W S Pierpoint
Jan 17, 2004·The Annals of Thoracic Surgery·Ayako MaruoHartzell V Schaff
Mar 20, 2004·Acta Cardiologica·Hangyuan GuoJian'an Wang
Aug 4, 2004·Medical Hypotheses·Lexin Wang, Guoqin Feng
Oct 8, 2004·The New England Journal of Medicine·Eric J Topol
Jan 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Clinton K Murray, Lynn L Horvath
Jul 28, 2007·The Journal of Biological Chemistry·Christine A HarmanR Michael Garavito
Mar 24, 2012·The Lancet Oncology·Annemijn M Algra, Peter M Rothwell
Jan 24, 2014·Molecular Plant-microbe Interactions : MPMI·Feng ZhuHong-Hui Lin
May 31, 2014·British Journal of Cancer·L AlfonsoG J Bhat
Citations
Mar 13, 2016·International Immunopharmacology·James E Talmadge
Mar 10, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Robin A Weiss, José Esparza
Jul 4, 2016·The Science of the Total Environment·Andreas SchaefferMartina Roß-Nickoll
Jan 21, 2017·British Journal of Haematology·Michael J R Desborough, David M Keeling
Aug 13, 2017·The Veterinary Record·P LeesM L Whitehead
Jun 5, 2019·The Journal of Animal Ecology·Emily G SimmondsBen C Sheldon
May 29, 2019·The American Journal of Bioethics : AJOB·Jake Earl
Nov 2, 2019·European Journal of Pharmacology·Jolanta HybiakElżbieta Urasińska
Aug 14, 2021·Ageing Research Reviews·Dorit Samocha-BonetDavid K Ryugo
Sep 14, 2021·Annual Review of Pharmacology and Toxicology·Kaitlyn E Redford, Geoffrey W Abbott