From the GPS to HM: Place cells, grid cells, and memory.

Hippocampus
James J Knierim

Abstract

A longstanding debate in hippocampus research has revolved around how to reconcile spatial mapping functions of the hippocampus with the global amnesia produced by hippocampal damage in humans. Is the hippocampus primarily a cognitive map used to support spatial learning, or does it support more general types of learning necessary for declarative memory? In recent years, a general consensus has emerged that the hippocampus receives both spatial and nonspatial inputs from the entorhinal cortex. The hippocampus creates representations of experience in a particular spatial and temporal context. This process allows the individual components of experience to be stored in such a way that they can be retrieved together as a conscious recollection.

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Citations

Nov 22, 2015·NeuroImage·Carmen VivarHenriette van Praag
May 13, 2017·Cold Spring Harbor Perspectives in Medicine·C'iana CooperHenriette van Praag
Dec 8, 2017·Frontiers in Neurorobotics·Taiping Zeng, Bailu Si
Oct 17, 2019·Annals of the New York Academy of Sciences·Jennifer D RyanZhong-Xu Liu
Dec 22, 2017·Hippocampus·Brad E Pfeiffer
Dec 13, 2017·Journal of Neuroscience Research·Michael J HylinPramod K Dash
Apr 14, 2021·Neuroscience and Biobehavioral Reviews·Hannah S Wirtshafter, Matthew A Wilson
Aug 29, 2021·Journal of Neuroscience Methods·Manu S MadhavNoah J Cowan

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