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From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

Acta Neuropathologica

Nov 4, 2019

Morvane ColinLuc BUEE

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Abstract

The term "propagon" is used to define proteins that may transmit misfolding in vitro, in tissues or in organisms. Among propagons, misfolded tau is thought to be involved in the pathogenic mechanisms of various "tauopathies" that include Alzheimer's disease, progressive supranuclear pal...read more

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Alzheimer's Disease
Biological Markers
Clinical Trials
Immunotherapy
Literature
Pathology
Research
Tau Proteins
Interstitial Fluid
Prion Diseases
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From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy

Acta Neuropathologica

Nov 4, 2019

Morvane ColinLuc BUEE

PMID: 31686182

DOI: 10.1007/s00401-019-02087-9

Abstract

The term "propagon" is used to define proteins that may transmit misfolding in vitro, in tissues or in organisms. Among propagons, misfolded tau is thought to be involved in the pathogenic mechanisms of various "tauopathies" that include Alzheimer's disease, progressive supranuclear pal...read more

Mentioned in this Paper

Alzheimer's Disease
Biological Markers
Clinical Trials
Immunotherapy
Literature
8
2
17

Similar Papers Found In These Feeds

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