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Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease

Journal of Neuroinflammation

Feb 19, 2020

Marta Moreno-RodriguezElliott J Mufson

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PubMed

Abstract

Chitinase 3-like 1 (CHI3L1), chitinase 3-like 2 (CHI3L2), and neuronal pentraxin II (NPTX2) are inflammatory biomarkers of Alzheimer's disease (AD). Although studies have demonstrated that cerebrospinal fluid levels of these proteins are changed in AD, no studies have undertaken a detai...read more

Mentioned in this Paper

Impaired Cognition
Study
Persons
NPTX2 gene
Inflammatory Response
Chitinase-3-Like Protein 1
NPTX2
Immunoblotting
Chromosome 1q
Protein Level - Finding
1
Paper Details
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Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease

Journal of Neuroinflammation

Feb 19, 2020

Marta Moreno-RodriguezElliott J Mufson

PMID: 32066474

DOI: 10.1186/s12974-020-1723-x

Abstract

Chitinase 3-like 1 (CHI3L1), chitinase 3-like 2 (CHI3L2), and neuronal pentraxin II (NPTX2) are inflammatory biomarkers of Alzheimer's disease (AD). Although studies have demonstrated that cerebrospinal fluid levels of these proteins are changed in AD, no studies have undertaken a detai...read more

Mentioned in this Paper

Impaired Cognition
Study
Persons
NPTX2 gene
Inflammatory Response
Chitinase-3-Like Protein 1
NPTX2
Immunoblotting
Chromosome 1q
Protein Level - Finding
1

Feeds With Similar Papers

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

International Journal of Biomedical Science : IJBS

Gene Encoding Chitinase 3-Like 1 Protein (CHI3L1) is a Putative Oncogene

International Journal of Biomedical Science : IJBSSeptember 1, 2011
Vadym M KavsanVladimir P Chekhonin
Paper Details
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