PMID: 2289137Oct 29, 1990Paper

Frontal lobe contribution to voluntary movements in humans

Brain Research
J Singh, R T Knight

Abstract

We assessed the contribution of human prefrontal cortex to movement related potentials (MRPs) generated prior to voluntary movements. MRPs were recorded during self-paced movements of the right thumb (experimental condition I), the left thumb (experimental condition II) and both thumbs (experimental condition III) from patients with focal lesions centered in dorsolateral frontal association cortex (PFCx, n = 11) and in age matched controls (n = 11). Controls generated a slowly rising readiness potential (RP) beginning at about 1000 ms prior to movement. A negative shift (NS') began at about 450 ms and a motor potential (MP) appeared at about 100 ms prior to movement. Both the NS' and MP were maximal over scalp sites contralateral to movements. Unilateral PFCx lesions preferentially reduced the RP and NS' components of the MRP. This indicates that PFCx is involved in a neural network beginning at least 1000 ms prior to movement. The differential PFCx effects on the early (RP, NS') and late components (MP) suggest that these MRPs index different movement-related circuits.

References

May 5, 1975·Brain Research·J Arezzo, H G Vaughan
Jun 25, 1990·Brain Research·S Yamaguchi, R T Knight
Apr 1, 1986·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Apr 1, 1987·Electroencephalography and Clinical Neurophysiology·R W HomanP Purdy
Dec 1, 1988·Electroencephalography and Clinical Neurophysiology·R T KnightC Clayworth
Dec 18, 1989·Brain Research·R T KnightD L Woods
Sep 25, 1989·Brain Research·R T KnightD L Woods
Feb 1, 1989·Brain : a Journal of Neurology·J P DickC D Marsden
Sep 1, 1988·Annals of Neurology·R NeshigeH Shibasaki
Feb 8, 1987·The Journal of Comparative Neurology·H Barbas, D N Pandya
Nov 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·L DeeckeH H Kornhuber
Mar 1, 1986·Psychophysiology·D T StussA M Cerri
Jan 1, 1986·Schizophrenia Bulletin·L Miller
Nov 1, 1985·Behavioural Brain Research·H J Freund
Sep 1, 1985·Brain : a Journal of Neurology·H J Freund, H Hummelsheim
Jan 1, 1985·Neuropsychologia·G W Jason
Dec 18, 1985·Neuroscience Letters·R BeneckeC D Marsden
Jun 1, 1971·Electroencephalography and Clinical Neurophysiology·D W McAdam, E H Rubin
Sep 1, 1973·Electroencephalography and Clinical Neurophysiology·J T Wilke, R W Lansing
May 1, 1966·Electroencephalography and Clinical Neurophysiology·L GildenL D Costa
Jul 1, 1968·Electroencephalography and Clinical Neurophysiology·H G VaughanW Ritter
Jul 1, 1969·Electroencephalography and Clinical Neurophysiology·D W McAdam, D M Seales
Jun 1, 1974·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·E A Drewe
Jan 1, 1969·Brain : a Journal of Neurology·E G Jones, T P Powell
Aug 1, 1971·Journal of Psychiatric Research·W J Nauta
Aug 1, 1980·Electroencephalography and Clinical Neurophysiology·H ShibasakiA M Halliday
Dec 1, 1981·Electroencephalography and Clinical Neurophysiology·R T KnightH J Neville
Sep 1, 1982·Electroencephalography and Clinical Neurophysiology·B LibetC A Gleason
Jan 1, 1984·Annals of the New York Academy of Sciences·L DeeckeR Kristeva
Sep 1, 1983·Experimental Neurology·R K Deuel, R C Collins
May 27, 1982·Brain Research·U Halsband, R Passingham

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Citations

Jan 3, 2001·Muscle & Nerve. Supplement·M J McKeown
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·S Oda, T Moritani
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·S Oda, T Moritani
Jan 1, 1995·European Journal of Applied Physiology and Occupational Physiology·S Oda, T Moritani
Nov 13, 2008·Cognitive Neurodynamics·Susan PockettWalter J Freeman
Nov 1, 1994·Electroencephalography and Clinical Neurophysiology·K AlhoR Näätänen
Oct 1, 1994·Electroencephalography and Clinical Neurophysiology·K B BöckerP J Cluitmans
Jun 1, 1996·Electroencephalography and Clinical Neurophysiology·L HultinV Pizzella
Mar 1, 1995·Electroencephalography and Clinical Neurophysiology·L L ChaoR T Knight
Oct 30, 1990·Neuroscience Letters·J SinghC Clayworth
Oct 1, 1992·Schizophrenia Research·J SinghD L Woods
Sep 5, 2002·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Kiyoto KasaiAkira Iwanami
Oct 17, 2003·Brain Research. Cognitive Brain Research·Minna Valkonen-KorhonenJohannes Lehtonen
Dec 1, 1996·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·S OdaT Moritani
Jun 1, 1997·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·M ShibataT Moritani
Dec 5, 1998·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·T Moritani, Y Yoshitake
Jan 28, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Holger WieseMatthias Keidel
Sep 1, 1998·Cognitive Neuropsychology·M Jahanshahi
Feb 18, 2005·Journal of Neurotrauma·F Di RussoP Zoccolotti
Apr 6, 2001·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·M J McKeown, R Radtke
Dec 17, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jürgen Kayser, Craig E Tenke
Jan 17, 2012·Neuropsychologia·Katharine S BakerRoss Cunnington
Sep 17, 1999·Consciousness and Cognition·K VogeleyW Maier
Nov 18, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Holger WieseMatthias Keidel
Nov 21, 2019·Journal of Neural Engineering·Kun WangDong Ming
May 18, 2017·Frontiers in Human Neuroscience·Kisun KimChun Kee Chung

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