Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm

American Journal of Physiology. Endocrinology and Metabolism
Boubacar Benziane, Alexander V Chibalin

Abstract

The skeletal muscle sodium pump plays a major role in the removal of K(+) ions from the circulation postprandial, or after a physical activity bout, thereby preventing the development of hyperkalemia and fatigue. Insulin and muscle contractions stimulate Na(+)-K(+)-ATPase activity in skeletal muscle, at least partially via translocation of sodium pump units to the plasma membrane from intracellular stores. The molecular mechanism of this phenomenon is poorly understood. Due to the contradictory reports in the literature, the very existence of the translocation of Na(+)-K(+)-ATPase to the skeletal muscle cell surface is questionable. This review summarizes more than 30 years work on the skeletal muscle sodium pump translocation paradigm. Furthermore, the methodological caveats of major approaches to study the sodium pump translocation in skeletal muscle are discussed. An understanding of the molecular regulation of Na(+)-K(+)-ATPase in skeletal muscle will have important clinical implications for the understanding of the development of complications associated with the metabolic syndrome, such as cardiovascular diseases or increased muscle fatigue in diabetic patients.

References

Jul 1, 1976·The Journal of Physiology·D Erlij, S Grinstein
Feb 1, 1977·The Journal of Physiology·T Clausen, P G Kohn
Jan 29, 1986·Biochemical and Biophysical Research Communications·M Kanbe, H Kitasato
Oct 1, 1988·The American Journal of Physiology·H Núñez-DuránL Bárcenas-Ruiz
Sep 6, 1974·Nature·S Grinstein, D Erlij
Jan 1, 1982·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·J F Lamb, P Ogden
Feb 1, 1995·The American Journal of Physiology·C J GottardiM J Caplan
Dec 24, 1997·Annals of the New York Academy of Sciences·L A DunbarM J Caplan
Apr 6, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·C JuelJ Bangsbo
May 24, 2000·Proceedings of the National Academy of Sciences of the United States of America·G A YudowskiA M Bertorello
Nov 20, 2001·Pflügers Archiv : European journal of physiology·C JuelT Wulff
Aug 10, 2002·Proceedings of the National Academy of Sciences of the United States of America·Gilles CrambertKathi Geering
Sep 25, 2003·Physiological Reviews·Torben Clausen
Apr 8, 2004·The Journal of Biological Chemistry·Lubna Al-KhaliliAlexander V Chibalin
Aug 20, 2005·Journal of Applied Physiology·S D E SandifordJ Ouyang
Sep 6, 2005·Seminars in Nephrology·Alicia A McDonough, Jang H Youn
May 23, 2006·The Journal of Biological Chemistry·Olga KotovaAlexander V Chibalin
Nov 10, 2007·The Journal of Biological Chemistry·Stéphanie BibertKäthi Geering
Nov 16, 2007·American Journal of Physiology. Cell Physiology·Dan ZhengAlicia A McDonough
Jan 8, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Joseph Y Cheung

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Citations

Jun 21, 2011·The Journal of Membrane Biology·Maria S IngwersenCarsten Juel
Jul 31, 2008·Pflügers Archiv : European journal of physiology·Krishna M BoiniFlorian Lang
May 23, 2012·The Journal of Biological Chemistry·Boubacar BenzianeAlexander V Chibalin
Sep 2, 2008·Annual Review of Physiology·Jang H Youn, Alicia A McDonough
Nov 5, 2010·American Journal of Physiology. Cell Physiology·Sandrine V PierreYoann Sottejeau
May 3, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kamel S KamelMitchell L Halperin
Nov 1, 2011·Clinical and Experimental Nephrology·Florian Lang, Volker Vallon
Jan 21, 2016·Acta Physiologica·Sergej Pirkmajer, Alexander V Chibalin
Jul 1, 2008·Experimental Physiology·K T MurphyT Clausen
Mar 10, 2017·American Journal of Physiology. Cell Physiology·Alexey M PetrovIgor I Krivoi
Jun 28, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Kevin Ho
Sep 9, 2008·American Journal of Physiology. Endocrinology and Metabolism·Torben Clausen
Jan 26, 2012·American Journal of Physiology. Endocrinology and Metabolism·Hanneke BoonAlexander V Chibalin
May 12, 2016·American Journal of Physiology. Endocrinology and Metabolism·Sergej Pirkmajer, Alexander V Chibalin
Jun 10, 2011·American Journal of Physiology. Endocrinology and Metabolism·Boubacar BenzianeAlexander V Chibalin
Jun 2, 2017·Molecular and Cellular Biochemistry·Aleksandra JovanovicEsma R Isenovic
Apr 16, 2009·American Journal of Physiology. Endocrinology and Metabolism·Dana GaluskaAlexander V Chibalin
Jun 19, 2012·Journal of Applied Physiology·Martin Broch-LipsCraig A Goodman
Jan 6, 2021·Journal of Muscle Research and Cell Motility·Sergej PirkmajerAlexander V Chibalin
Feb 21, 2021·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Christopher D MoyesR Meldrum Robertson
Jul 28, 2020·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·J D GantzRichard E Lee

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