Frozen pulp extracts of camu-camu (Myrciaria dubia McVaugh) attenuate the hyperlipidemia and lipid peroxidation of Type 1 diabetic rats

Food Research International
Any Elisa de Souza Schmidt GonçalvesMaria Inés Genovese

Abstract

Several epidemiological and experimental studies demonstrate that modulation of inflammatory response and oxidative stress by natural phytochemicals is a promising strategy to prevent and treat many chronic inflammatory diseases. Camu-camu is an Amazonian fruit with a high content of antioxidants, especially phenolic compounds and vitamin C. In the present study we evaluated the in vivo effects of chronic ingestion of raw extracts derived from camu-camu (Myrciaria dubia McVaugh) frozen pulp on plasma lipid profile and oxidative stress in streptozotocin-induced diabetic rats. Oral administration of camu-camu raw extracts significantly increased plasma antioxidant activity, reduced triacylglycerol and total cholesterol and lipid peroxidation in the plasma of streptozotocin-induced diabetic rats. However, no effect was observed on glucose metabolism of diabetic rats, probably due to the severity of this model.

Citations

Sep 12, 2019·Revista do Colégio Brasileiro de Cirurgiões·Hercules Magalhães Olivense do CarmoRomeu Paulo Martins Silva
Nov 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marina FidelisDaniel Granato
Jul 15, 2020·Critical Reviews in Food Science and Nutrition·Sima Maleki, Seyed Hadi Razavi
Mar 27, 2019·Oxidative Medicine and Cellular Longevity·Raúl Avila-SosaAddí Rhode Navarro-Cruz
Dec 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Natália ConceiçãoIsabel C F R Ferreira
Apr 22, 2015·Molecular and Cellular Biochemistry·Nicéia Spanholi CalgarotoMaria Rosa Chitolina Schetinger
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Jul 29, 2018·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Marina FidelisDaniel Granato

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