Frozen red cells in Rhesus immunization

British Journal of Haematology
I A CookA E Robertson


The use of frozen washed cells in varying doses in primary Rh immunization is compared to two groups of men with the use of fresh washed cells in a third group. In the first two groups, using frozen cells, doses ranging from 0.5 to 20 ml of whole blood (Group I) are compared with a 200.0 ml dose of red cell concentrate (Group II), while Group III served as a control using a 20 ml dose of fresh washed red cell suspension (9.0 ml concentrated red cell equivalent). The response rate was 93% in Group II compared with only 43% in Group I, suggesting the desirability of using relatively large doses of Rh-positive red cells for primary Rh immunization. The use of frozen washed cells from a special panel for 'booster' injections is also recommended.


Jan 20, 1979·Lancet·H H Gunson, D P Thomas
Mar 1, 1978·British Journal of Haematology·D R BanghamH H Gunson
Mar 1, 1976·British Journal of Haematology·H H GunsonP K Phillips
Mar 1, 1976·British Journal of Haematology·H H GunsonP K Phillips
May 1, 1974·British Journal of Haematology·H H GunsonP K Phillips
Mar 1, 1972·Journal of Clinical Pathology·H H GunsonF Stratton
Jun 1, 1973·Journal of Clinical Pathology·R MitchellE A McLaren
Mar 7, 1970·British Medical Journal·H H GunsonV I Rawlinson
Apr 1, 1971·British Journal of Haematology·I A Cook
Dec 1, 1971·British Journal of Haematology·H H GunsonP K Phillips
Jun 1, 1972·Journal of Clinical Pathology·R Mitchell, W Muir

Related Concepts

Blood Preservation
Dose-Response Relationship, Immunologic
Antigen D, Rh Blood Group

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