Fructose, exercise, and health.

Current Sports Medicine Reports
Richard J Johnson, Robert Murray

Abstract

The large daily energy intake common among athletes can be associated with a large daily intake of fructose, a simple sugar that has been linked to metabolic disorders. Fructose commonly is found in foods and beverages as a natural component (e.g., in fruits) or as an added ingredient (as sucrose or high fructose corn syrup [HFCS]). A growing body of research suggests that excessive intake of fructose (e.g., >50 g.d(-1)) may be linked to development of the metabolic syndrome (obesity, dyslipidemia, hypertension, insulin resistance, proinflammatory state, prothrombosis). The rapid metabolism of fructose in the liver and resultant drop in hepatic adenosine triphosphate (ATP) levels have been linked with mitochondrial and endothelial dysfunction, alterations that could predispose to obesity, diabetes, and hypertension. However, for athletes, a positive aspect of fructose metabolism is that, in combination with other simple sugars, fructose stimulates rapid fluid and solute absorption in the small intestine and helps increase exogenous carbohydrate oxidation during exercise, an important response for improving exercise performance. Although additional research is required to clarify the possible health-related implications of long-...Continue Reading

References

Apr 1, 1975·The Journal of Clinical Investigation·J S Fordtran
Aug 1, 1972·Metabolism: Clinical and Experimental·I H Fox, W N Kelley
May 1, 1968·The Journal of Clinical Investigation·W A Olsen, F J Ingelfinger
Jan 1, 1980·Journal of Agricultural and Food Chemistry·S Nagy
Apr 1, 1995·Journal of Diabetes and Its Complications·Y TakagiY Shigeta
Aug 26, 2004·JAMA : the Journal of the American Medical Association·Matthias B SchulzeFrank B Hu
Sep 9, 2004·Medicine and Science in Sports and Exercise·Roy L P G JentjensAsker E Jeukendrup
Jan 13, 2005·The Journal of Pediatrics·Sibylle KranzDiane Mitchell
May 7, 2005·Metabolism: Clinical and Experimental·Roy L P G JentjensAsker E Jeukendrup
Jun 11, 2005·The British Journal of Nutrition·Roy L P G Jentjens, Asker E Jeukendrup
Oct 20, 2005·American Journal of Physiology. Renal Physiology·Takahiko NakagawaRichard J Johnson
Feb 3, 2006·Pediatrics·Samuel S GiddingUNKNOWN American Heart Association
Aug 31, 2006·American Journal of Physiology. Renal Physiology·Laura G Sánchez-LozadaMartha Franco
Apr 13, 2007·American Journal of Physiology. Cell Physiology·Yuri Y SautinRichard J Johnson
Aug 3, 2007·American Journal of Physiology. Renal Physiology·Michael S GerschTakahiko Nakagawa
Jan 25, 2008·American Journal of Physiology. Renal Physiology·Laura G Sánchez-LozadaRichard J Johnson
Apr 9, 2008·Journal of Hepatology·Xiaosen OuyangManal F Abdelmalek
Jul 24, 2008·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Richard J JohnsonSteven A Benner

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Citations

Dec 13, 2016·Journal of Physical Therapy Science·Filiz Fatma ColakogluFatmanur Er
Mar 9, 2018·The Journal of Experimental Biology·Luc Tappy
Dec 3, 2016·Journal of Applied Physiology·Angela SunDong Sun
Feb 16, 2016·Biochemistry. Biokhimii︠a︡·A I KuzmenkovA A Vassilevski
Dec 12, 2013·American Journal of Physiology. Endocrinology and Metabolism·Veeraj GoyaramEdward O Ojuka
Jun 22, 2016·European Journal of Nutrition·James M Rippe, Ascensión Marcos
Jan 21, 2021·Journal of Functional Morphology and Kinesiology·Francesca CannataNicola Napoli

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