Fructose malabsorption

Molecular and Cellular Pediatrics
Karolin Ebert, Heiko Witt

Abstract

Incomplete intestinal absorption of fructose might lead to abdominal complaints such as pain, flatulence and diarrhoea. Whether defect fructose transporters such as GLUT5 or GLUT2 are involved in the pathogenesis of fructose malabsorption is a matter of debate. The hydrogen production by colonic bacteria is used for diagnosis with the hydrogen breath test. However, the appropriate fructose test dose for correct diagnosis is unclear. Subjects with fructose malabsorption show increased breath hydrogen levels and abdominal symptoms after fructose administration but do not report any symptoms when fructose is given together with glucose. This beneficial effect of glucose, however, cannot be explained yet but might be used for clinical care of these subjects.

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Citations

Feb 9, 2017·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Ricardo J S CostaPeter Gibson
Sep 8, 2017·Nutrients·Kasper W Ter Horst, Mireille J Serlie
Mar 29, 2018·The British Journal of Nutrition·Luanne R DeChristopher, Katherine L Tucker
Mar 29, 2019·Chronobiology International·Shumin SunHiroaki Oda
Jul 2, 2019·Journal of Pediatric Gastroenterology and Nutrition·Chantal Florence MeierRaphael Nicolas Vuille-Dit-Bille
May 17, 2017·Scandinavian Journal of Medicine & Science in Sports·A MiallR J S Costa
Aug 16, 2016·Molecular and Cellular Pediatrics·Hassan Y NaimBuford Nichols
May 6, 2021·Nutrients·Inés Bravo-RuizBeatriz Martínez-Poveda
Aug 28, 2019·Clinical Nutrition ESPEN·Xin Qi, Richard F Tester
Jul 23, 2021·Journal of Pediatric Gastroenterology and Nutrition·Ilse Julia BroekaertMarc Benninga

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