Fuchs' corneal dystrophy.

Expert Review of Ophthalmology
Allen O Eghrari, John D Gottsch

Abstract

Fuchs' corneal dystrophy (FCD) is a progressive, hereditary disease of the cornea first described a century ago by the Austrian ophthalmologist Ernst Fuchs. Patients often present in the fifth to sixth decade of life with blurry morning vision that increases in duration as the disease progresses. Primarily a condition of the posterior cornea, characteristic features include the formation of focal excrescences of Descemet membrane termed 'guttae', loss of endothelial cell density and end-stage disease manifested by corneal edema and the formation of epithelial bullae. Recent advances in our understanding of the genetic and pathophysiological mechanisms of the disease, as well as the application of new imaging modalities and less invasive surgical procedures, present new opportunities for improved outcomes among patients with FCD.

References

May 1, 1975·The American Journal of Physiology·S D Klyce
Nov 1, 1978·Archives of Ophthalmology·J H KrachmerK D Bucher
Nov 1, 1978·Survey of Ophthalmology·G O WaringP R Laibson
Oct 1, 1979·Ophthalmology·M MagovernR C Baumiller
Mar 1, 1978·The British Journal of Ophthalmology·L E OlsonR Andrews
Jun 1, 1976·Experimental Eye Research·R A LaingH M Leibowitz
Jun 1, 1976·American Journal of Ophthalmology·G O WaringR D Mulberger
Oct 1, 1992·Archives of Ophthalmology·N MamalisR J Olson
Aug 1, 1992·Archives of Ophthalmology·K K WilliamsH F Edelhauser
Aug 1, 1991·The British Journal of Ophthalmology·A LoewensteinM Lazar
May 1, 1991·Cornea·T D LindquistJ W Chandler
Jan 1, 1989·Eye·R J Morris, A K Bates
May 15, 1989·American Journal of Ophthalmology·P MohamadiR E Smith
Aug 15, 1989·American Journal of Ophthalmology·S E BradyP R Laibson
Apr 1, 1987·Human Pathology·S I RothR Jutabha
Jan 1, 1985·Archives of Ophthalmology·M MatsudaH F Edelhauser
Feb 1, 1972·The Journal of Physiology·D M Maurice
Mar 1, 1971·Archives of Ophthalmology·H E CrossS J Cantolino
Mar 1, 1968·Archives of Ophthalmology·T KuwabaraD G Cogan
Jan 1, 1984·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·T Olsen
Oct 1, 1980·American Journal of Ophthalmology·P RosenblumA E Maumenee
Dec 1, 1982·Archives of Ophthalmology·W M BourneR J Campbell
Aug 1, 1982·The British Journal of Ophthalmology·R S Wilson, M J Roper-Hall
Dec 1, 1982·Archives of Ophthalmology·D H JohnsonR J Campbell
Aug 1, 1994·Acta Ophthalmologica·P HaamannP Schmidt
Jan 1, 1996·Archives of Ophthalmology·O PinerosP R Laibson
Nov 1, 1995·Cornea·C W FlowersR E Smith
May 1, 1996·Archives of Ophthalmology·O E PinerosP R Laibson
Apr 16, 1998·Journal of Medical Genetics·R L Albin
Oct 2, 1998·Cornea·R K MustonenC K Kim
Nov 20, 1998·Cornea·G R MellesP S Binder
Jul 9, 1999·The British Journal of Ophthalmology·A G ChiouH E Kaufman
Mar 29, 2001·Experimental Eye Research·M K KoJ G Chi
Jul 18, 2001·International Ophthalmology·S K RaoP Padmanabhan
Nov 16, 2001·Archives of Ophthalmology·Q J LiT P O'Brien
Feb 28, 2002·Cornea·Matthew EdwardsCharles N J McGhee
Jan 31, 2003·Investigative Ophthalmology & Visual Science·John D GottschSammy H Liu
Mar 19, 2003·The British Journal of Ophthalmology·T LietmanS Costanza

❮ Previous
Next ❯

Citations

Dec 19, 2013·BioMed Research International·Katarzyna A WójcikJacek P Szaflik
Apr 16, 2013·Expert Review of Ophthalmology·Benjamin W IliffJohn D Gottsch
Aug 26, 2014·International Journal of Molecular Sciences·Katarzyna A WojcikJacek P Szaflik
Aug 23, 2011·Experimental Eye Research·Thore SchmedtUla Jurkunas
Sep 22, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Katarzyna A WójcikJacek P Szaflik
Jul 24, 2015·Cellular & Molecular Biology Letters·Katarzyna A WojcikJacek P Szaflik
Oct 22, 2013·Seminars in Ophthalmology·Cecily E HamillUla Jurkunas
Apr 14, 2016·Ophthalmology and Therapy·Vincent S HauMichelle Dalton
Aug 30, 2014·The Tohoku Journal of Experimental Medicine·Ewelina SynowiecJacek P Szaflik
Apr 12, 2017·Current Opinion in Ophthalmology·C Maya TongGerrit R J Melles
Sep 26, 2013·International Journal of Molecular Sciences·Katarzyna A WojcikJacek P Szaflik
Apr 1, 2018·Journal of Biophotonics·Iliya V IvanovSiegfried Wahl
Dec 7, 2017·Indian Journal of Ophthalmology·Namrata SharmaPrafulla Kumar Maharana
Oct 5, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Nicholas S ReedJohn D Gottsch
Sep 27, 2018·Cornea·Takashi Miyai
Jul 14, 2018·Eye & Contact Lens·Caterina SarnicolaKathryn Colby
Nov 11, 2019·Scientific Reports·Peipei PanMatilda F Chan
Jul 24, 2020·European Journal of Ophthalmology·Christian M WertheimerWolfgang J Mayer
Dec 19, 2018·Therapeutic Advances in Ophthalmology·Sepehr Feizi
Jun 25, 2020·International Ophthalmology Clinics·Victoria S ChangCarla Osigian
Sep 11, 2020·The British Journal of Ophthalmology·Victor A AugustinTheofilos Tourtas
Dec 8, 2017·Journal of Modern Optics·Devrim ToslakXincheng Yao
Nov 1, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rohan P BajajAllen O Eghrari
Dec 2, 2020·Investigative Ophthalmology & Visual Science·Marcus WalcklingSimone Baltrusch
May 22, 2020·Progress in Retinal and Eye Research·Stephan Ong ToneUla V Jurkunas
Aug 19, 2017·Cornea·Julia Furtado HeringerPedro Carlos Carricondo
Feb 18, 2021·Experimental Eye Research·Lauren J JeangEdgar M Espana
Feb 23, 2021·Experimental Eye Research·Isabelle XuStéphanie Proulx
Aug 1, 2020·Progress in Retinal and Eye Research·Michael P FautschAlice E Davidson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved