Fucoidanases

Glycobiology
Mikhail KusaykinT N Zvyagintseva

Abstract

In recent years, the research of fucoidans has steadily increased. The interest in these substances is due to their various biological activities. Despite a wide range of biological activity and the lack of oral toxicity, fucoidans remain relatively unexploited as a source of medicines because of their heterogeneity. Enzymes that degrade polyanionic polysaccharides are widely used for establishing their structures and structure-activity relationships. Sometimes, to obtain preparations of polysaccharides with standard characteristics, for example, medicines and food supplements, enzymatic treatment can be also applied. Only a few sources of enzymes with fucoidanase activity have been described, and only a few studies regarding the isolation and characterization of fucoidanases have been performed. The data on the specificity of fucoidanases: the type of cleaved glycoside bond, the relation between catalytic activity and the degree of substrate sulfation are scarce. The review summarizes achievements in the research of fucoidanases, mechanisms of enzymatic degradation of fucoidans, as well as of structures of sulfated fucooligosaccharides obtained under the action of fucoidanases.

References

Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·B HenrissatG Davies
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Sep 7, 2000·Thrombosis Research·T NishinoH Suzuki
Mar 20, 2001·Nature Reviews. Molecular Cell Biology·U TepassM Peifer
Apr 13, 2002·Carbohydrate Research·Maria I BilanAnatolii I Usov
Dec 19, 2003·Nucleic Acids Research·Alex BatemanSean R Eddy
Feb 13, 2004·Marine Biotechnology·Takeshi SakaiIkunoshin Kato
Apr 14, 2004·Current Pharmaceutical Design·Paulo A S Mourão
Sep 7, 2005·FEMS Microbiology Letters·Lihuan CaoLong Yu
Oct 14, 2005·Marine Biotechnology·Valérie DescampsBernard Kloareg
Sep 1, 1990·Applied and Environmental Microbiology·M KitamikadoB Okabe
Jun 11, 2008·Biotechnology Journal·Mikhail KusaykinTatyana Zvyagintseva
Sep 17, 2008·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bo LiRuixiang Zhao
Dec 2, 2008·Applied Microbiology and Biotechnology·Andrea Désirée HoltkampSiegmund Lang
Dec 22, 2009·Journal of Bacteriology·Milana FraibergRaphael Lamed
Jan 15, 2010·Letters in Applied Microbiology·Y ChangJ Wang
May 26, 2010·Applied Biochemistry and Biotechnology·Rosa M Rodríguez-JassoJosé A Teixeira
Aug 12, 2010·Bioscience, Biotechnology, and Biochemistry·Takashi OhshiroYoshikazu Izumi
Feb 9, 2011·Applied Biochemistry and Biotechnology·Svetlana ErmakovaTatyana Zvyagintseva
Oct 7, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Wu QianqianCai Jingmin
May 12, 2012·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Soon-Ki MinJong-Ki Kim
Oct 10, 2012·Carbohydrate Polymers·Weihua JinWenjing Zhang
Jul 16, 2013·Marine Drugs·Artem S SilchenkoTatyana N Zvyagintseva
Jul 17, 2013·Marine Drugs·Nadezhda E UstyuzhaninaNikolay E Nifantiev
Sep 10, 2013·Biochemistry. Biokhimii︠a︡·V V SovaT N Zvyagintseva
Jun 1, 2014·International Journal of Biological Macromolecules·Qifei CongKan Ding
Jan 1, 1992·Bioscience, Biotechnology, and Biochemistry·K KitamuraY Tsuneo

❮ Previous
Next ❯

Citations

Jul 28, 2018·Frontiers in Microbiology·Larissa BalabanovaLiudmila Tekutyeva
Mar 22, 2020·Marine Drugs·Ahmed Zayed, Roland Ulber
Jan 6, 2021·Applied and Environmental Microbiology·Magnus Ø ArntzenVincent G H Eijsink

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Glycosides

Cardiac glycosides are a diverse family of naturally derived compounds that bind to and inhibit na+/k+-atpase. Discover the latest research on cardiac glycosides heres.

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.