Full genome analysis of a European-type genotype 3 hepatitis E virus variant obtained from a Japanese patient with autochthonous acute hepatitis E

Journal of Medical Virology
Suguru TakeuchiHiroaki Okamoto

Abstract

A unique European-type HEV strain (HE-JA12-0725) classifiable into subgenotype 3f was recovered from a 66-year-old Japanese female with autochthonous acute hepatitis E, and its entire genomic sequence was determined and characterized. The HE-JA12-0725 strain shared the highest identity of 92.7% with a Spanish swine isolate (EU723514) over the entire genome and possessed a long hypervariable region sequence of 111 amino acids, identical to the 3f strains of European origin. The patient had consumed pork liver obtained via home delivery in Japan approximately two months before the disease onset. These results suggest the circulation of rare 3f HEV strains in Japan.

References

Dec 14, 2001·Biochemical and Biophysical Research Communications·H OkamotoA Yoshikawa
Aug 9, 2003·Lancet·Shuchin TeiShunji Mishiro
Feb 21, 2006·Emerging Infectious Diseases·Tian-Cheng LiTatsuo Miyamura
Mar 17, 2007·Virus Research·Hiroaki Okamoto
Jan 1, 2009·Emerging Infectious Diseases·Florence Legrand-AbravanelJacques Izopet
Feb 25, 2009·Journal of Medical Virology·Uamporn SiripanyaphinyoPathom Sawanpanyalert
Jun 27, 2009·Vox Sanguinis·C AdlhochH Meisel
Jan 13, 2010·The American Journal of Tropical Medicine and Hygiene·Maria Luisa Mateos LindemannMaria Teresa Pérez Gracia
Jul 16, 2010·Archives of Virology·Kamol SuwannakarnYong Poovorawan
Nov 28, 2012·Virus Genes·Juthatip KeawcharoenYong Poovorawan
Apr 9, 2013·Seminars in Liver Disease·Xiang-Jin Meng
Jun 1, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Masaharu Takahashi, Hiroaki Okamoto
Jun 19, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Tatsunori NakanoShunji Mishiro
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Oct 24, 2014·Journal of Clinical Microbiology·Barbara DoudierPhilippe Colson

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Citations

Jun 21, 2016·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yuichi YamazakiMasanobu Yamada

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