Full siblings impersonating parent/child prove most difficult to discredit with DNA profiling alone

Transfusion
Wing K FungYue-Qing Hu

Abstract

DNA profiling is currently the most widely used method for parentage verification, although many forms of it have limitations of some sort. In this paper, a general formula is derived to depict a simple relationship between the probability that a random man and the probably that a male relative of the child, other than the child's father, is excluded from paternity, when the phenotype of the child's mother is unavailable. With this, the possible limitations of a finite set of STR loci in excluding close relatives of the child from paternity are illustrated. Genetically, among the commonly encountered biologic relationships, to exclude a full sibling of the child from paternity if they pose themselves as father and child remains the most difficult.

References

Mar 1, 1996·Transfusion·R E WenkF A Chiafari
Sep 16, 2000·Transfusion·J B Gorlin, H F Polesky
May 18, 2001·International Journal of Legal Medicine·D M WongC T Chiu
Jan 5, 2002·International Journal of Legal Medicine·J A ThomsonP G Debenham
Jun 12, 2002·International Journal of Legal Medicine·Wing K FungDart-man Wong
Oct 12, 2002·Transfusion·M C A De UngriaS C Halos
Feb 20, 2003·International Journal of Legal Medicine·Yue-Qing Hu, Wing K Fung
Jun 26, 2003·Transfusion·Robert E WenkHerbert F Polesky
Jun 27, 2003·International Journal of Legal Medicine·Yue-Qing Hu, Wing K Fung

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Citations

Jun 7, 2005·Forensic Science International : Synergy·Yue-Qing Hu, Wing K Fung
Sep 1, 2007·Indian Journal of Human Genetics·A K Sharma
May 12, 2010·Forensic Science International. Genetics·Claus Børsting, Niels Morling
May 26, 2007·Transfusion·Debora SilveiraMartin R Whittle
Sep 7, 2005·Forensic Science International : Synergy·Nicole von Wurmb-SchwarkMicaela Poetsch

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