Fully automatic segmentation and objective assessment of atrial scars for long-standing persistent atrial fibrillation patients using late gadolinium-enhanced MRI

Medical Physics
Guang YangDavid N Firmin

Abstract

Atrial fibrillation (AF) is the most common heart rhythm disorder and causes considerable morbidity and mortality, resulting in a large public health burden that is increasing as the population ages. It is associated with atrial fibrosis, the amount and distribution of which can be used to stratify patients and to guide subsequent electrophysiology ablation treatment. Atrial fibrosis may be assessed noninvasively using late gadolinium-enhanced (LGE) magnetic resonance imaging (MRI) where scar tissue is visualized as a region of signal enhancement. However, manual segmentation of the heart chambers and of the atrial scar tissue is time consuming and subject to interoperator variability, particularly as image quality in AF is often poor. In this study, we propose a novel fully automatic pipeline to achieve accurate and objective segmentation of the heart (from MRI Roadmap data) and of scar tissue within the heart (from LGE MRI data) acquired in patients with AF. Our fully automatic pipeline uniquely combines: (a) a multiatlas-based whole heart segmentation (MA-WHS) to determine the cardiac anatomy from an MRI Roadmap acquisition which is then mapped to LGE MRI, and (b) a super-pixel and supervised learning based approach to delin...Continue Reading

References

Jun 14, 2002·Cardiovascular Research·Maurits AllessieUlrich Schotten
Aug 27, 2005·IEEE Transactions on Pattern Analysis and Machine Intelligence·Hanchuan PengChris Ding
May 1, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Hua ZhongDavid Schwartzman
Feb 12, 2008·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·P Thévenaz, M Unser
Feb 21, 2009·IEEE Transactions on Medical Imaging·Xabier ArtaechevarriaCarlos Ortiz-de-Solorzano
Feb 23, 2010·IEEE Transactions on Bio-medical Engineering·Benjamin R KnowlesKawal S Rhode
Apr 10, 2010·IEEE Transactions on Medical Imaging·Xiahai ZhuangSebastien Ourselin
Jun 22, 2010·IEEE Transactions on Medical Imaging·Mert R SabuncuPolina Golland
Nov 4, 2010·Journal of Cardiovascular Electrophysiology·Gaston R Vergara, Nassir F Marrouche
Nov 6, 2010·International Journal of Biomedical Imaging·Xujiong YeGreg Slabaugh
Jan 8, 2011·Journal of the American College of Cardiology·Rukshen WeerasooriyaPierre Jais
Mar 2, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mehdi H MoghariReza Nezafat
May 10, 2011·IEEE Transactions on Medical Imaging·Xiahai ZhuangSebastien Ourselin
Sep 29, 2011·NeuroImage·Simon F EskildsenUNKNOWN Alzheimer's Disease Neuroimaging Initiative
May 30, 2012·IEEE Transactions on Pattern Analysis and Machine Intelligence·Radhakrishna AchantaSabine Süsstrunk
Jun 27, 2012·IEEE Transactions on Pattern Analysis and Machine Intelligence·Hongzhi WangPaul A Yushkevich
Apr 23, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jennifer KeeganDavid N Firmin
May 21, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·L C Malcolme-LawesN S Peters
Aug 24, 2013·Journal of Healthcare Engineering·Xiahai Zhuang
Dec 24, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Rashed KarimKawal Rhode
Dec 24, 2013·Circulation. Arrhythmia and Electrophysiology·Christopher McGannNassir F Marrouche
Feb 6, 2014·JAMA : the Journal of the American Medical Association·Nassir F MarroucheJohannes Brachmann
May 13, 2014·JACC. Cardiovascular Imaging·Felipe BisbalLluís Mont
Jun 4, 2014·IEEE Transactions on Medical Imaging·Yao WuQianjin Feng
Oct 10, 2014·Medical Image Analysis·Wenjia BaiDaniel Rueckert
Dec 3, 2014·NeuroImage·Guorong WuUNKNOWN Alzheimer's Disease Neuroimaging Initiative
Feb 11, 2015·IEEE Transactions on Medical Imaging·Catalina Tobon-GomezKawal S Rhode
Jul 16, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Guang YangThomas R Barrick

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Citations

Nov 2, 2019·AJR. American Journal of Roentgenology·Qian TaoRob J van der Geest
Jun 9, 2020·Expert Review of Medical Devices·Andrew LinDamini Dey
Mar 21, 2020·Frontiers in Cardiovascular Medicine·Chen ChenDaniel Rueckert
Nov 4, 2020·Cardiovascular Engineering and Technology·Marija HabijanAleksandra Pižurica
Dec 8, 2019·Medical Image Analysis·Lei LiXiahai Zhuang
Jun 17, 2021·La Radiologia medica·Jason CraftJie Jane Cao

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