Fully optimized discrimination of physiological responses to auditory stimuli.

Journal of Neural Engineering
Stepan Y KruglikovSteven J Schiff

Abstract

The use of multivariate measurements to characterize brain activity (electrical, magnetic, optical) is widespread. The most common approaches to reduce the complexity of such observations include principal and independent component analyses (PCA and ICA), which are not well suited for discrimination tasks. We addressed two questions: first, how do the neurophysiological responses to elongated phonemes relate to tone and phoneme responses in normal children, and, second, how discriminable are these responses. We employed fully optimized linear discrimination analysis to maximally separate the multi-electrode responses to tones and phonemes, and classified the response to elongated phonemes. We find that discrimination between tones and phonemes is dependent upon responses from associative regions of the brain apparently distinct from the primary sensory cortices typically emphasized by PCA or ICA, and that the neuronal correlates corresponding to elongated phonemes are highly variable in normal children (about half respond with neural correlates of tones and half as phonemes). Our approach is made feasible by the increase in computational power of ordinary personal computers and has significant advantages for a wide range of neu...Continue Reading

References

Jul 1, 1978·Acta Psychologica·R NäätänenS Mäntysalo
Nov 1, 1995·Neural Computation·A J Bell, T J Sejnowski
May 1, 1993·Neuroreport·R NäätänenP Paavilainen
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·S MakeigT J Sejnowski
Aug 26, 1998·Psychophysiology·J KayserG E Bruder
May 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·S NagarajanM M Merzenich
Aug 18, 2000·Neural Networks : the Official Journal of the International Neural Network Society·A Hyvärinen, E Oja
Oct 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·P K Kuhl
Oct 4, 2005·NeuroImage·Steven J SchiffSteven L Weinstein
Dec 7, 2007·Journal of Neural Engineering·Apostolos P GeorgopoulosJoseph J Westermeyer

❮ Previous
Next ❯

Citations

Jul 21, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Joel S Snyder, Edward W Large
Dec 7, 2007·Journal of Neuroscience Methods·J McCubbinH Preissl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Brain-Computer Interface

A brain-computer interface, also known as a brain-machine interface, is a bi-directional communication pathway between an external device and a wired brain. Here is the latest research on this topic.