Fulminant type 1 diabetes mellitus and fulminant viral myocarditis. A case report and literature review

International Heart Journal
Nobumasa OharaKyuzi Kamoi

Abstract

A 35-year-old Japanese woman was admitted with coma following flu-like symptoms. She was diagnosed with diabetic ketoacidosis and fulminant type 1 diabetes (FT1D) and received intravenous infusion of insulin and saline. The next day, the ketoacidosis disappeared, and she recovered consciousness. However, extensive ST-segment elevations in the electrocardiogram appeared with a positive troponin test, and the patient developed pulmonary edema on day 3. An echocardiogram showed globally reduced wall motion of the left ventricle and mild pericardial effusion. Despite medical therapy with intravenous furosemide, carperitide, and catecholamines, her cardiac function deteriorated rapidly, with the left ventricular ejection fraction decreasing to 26% within 7 hours, and progressed to cardiogenic shock that afternoon. The patient received mechanical circulatory support for 4 days with intra-aortic balloon pumping and percutaneous cardiopulmonary support, and recovered fully from circulatory failure. A paired serum antibody test showed a significantly elevated titer against parainfluenza-3 virus, indicating a diagnosis of fulminant viral myocarditis. She was discharged on multiple daily insulin injection therapy, and her subsequent clini...Continue Reading

References

May 10, 1978·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·F OtsuM Yokota
Dec 1, 1994·British Heart Journal·A MatsumoriS Sasayama
May 1, 1996·Circulation Research·T KandaI Kobayashi
Apr 1, 1996·Diabetes Care·T MokunoA Nagasaka
Aug 29, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D Wilks, S M Burns
Sep 8, 1999·Circulation·R NishioS Sasayama
Sep 11, 2001·Journal of Molecular and Cellular Cardiology·D L Mann
Apr 15, 2003·Clinical Microbiology Reviews·Kelly J Henrickson
Dec 4, 2003·The New England Journal of Medicine·Kyuhyun WangHenry J L Marriott
Sep 15, 2004·Journal of the American College of Cardiology·Mototsugu NishiiTohru Izumi
Jan 12, 2005·European Journal of Heart Failure·Koichi FuseYoshifusa Aizawa
Feb 16, 2006·International Heart Journal·Takashi TakahashiTsugiyasu Kanda
Mar 29, 2006·Diabetologia·E KawasakiK Eguchi
Jul 29, 2006·Endocrine Journal·Akihisa Imagawa, Toshiaki Hanafusa
Oct 24, 2007·European Heart Journal·Kristian ThygesenUNKNOWN Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction
Nov 1, 2007·European Journal of Immunology·Charles A Dinarello
Sep 18, 2008·Nature Clinical Practice. Cardiovascular Medicine·Sachin GuptaPradeep Pa Mammen
Dec 25, 2008·Circulation·Yoshihiro J AkashiTakashi Ueyama
Oct 9, 2009·Diabetologia·Y KawabataUNKNOWN Committee on Type 1 Diabetes, Japan Diabetes Society
Feb 10, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
May 10, 2011·Endocrine Journal·Shinsuke HiramatsuSeiya Kato
Dec 22, 2011·Lancet·Sandeep SagarLeslie T Cooper

❮ Previous
Next ❯

Citations

Oct 1, 2015·Case Reports in Medicine·Mark A WeinreichRobert W Haley
Dec 6, 2017·Case Reports in Infectious Diseases·Cristina Aranda CazónJosé Tomás Ramos Amador
Nov 27, 2018·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Giovanni PerettoPaolo Della Bella

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.