Fumonisin B(1) and implications in nursery swine productivity: a quantitative exposure assessment

Journal of Animal Science
James E Delgado, Jeffrey D Wolt

Abstract

This study estimated the long-term exposure of fumonisin B(1) (FB(1)) in nursery swine diets and associated toxicological adverse effects on negative productivity potential using quantitative exposure assessment. Fumonisin B(1) is a mycotoxin produced by Fusarium verticillioides and Fusarium proliferatum and is a common biological contaminant of corn (Zea mays L.) and other grains. Acute effects from FB(1) exposures are well recognized and managed in the swine industry, but practices to limit prolonged low-dose exposures to FB(1) have been less fully considered and may negatively affect production efficiency. Deterministic (single-point estimates) and stochastic (probabilistic) modeling were performed for comparative analyses of FB(1) exposures originating from genetically engineered Bacillus thuringiensis (Bt)-corn, conventional non-Bt corn, and distillers dried grains with solubles (DDGS). Six feeding scenarios differing in the source of corn in diets were modeled to assess variation in FB(1) exposure representing a mixture of 1) Bt and non-Bt grain and DDGS (blended); 2) Bt grain and Bt DDGS; 3) non-Bt grain and non-Bt DDGS; 4) Bt and non-Bt grain; 5) Bt grain; and 6) non-Bt grain. Long-term exposure estimates (49-d duration...Continue Reading

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