Function and clinical potential of microRNAs in hepatocellular carcinoma

Oncology Letters
Lijuan WangHongchuan Jin

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs involved in the initiation and progression of several types of human cancer, including hepatocellular carcinoma (HCC), which is one of the most common types of cancer and the third leading cause of cancer-related mortality worldwide. Mounting evidence has demonstrated that miRNAs play a vital role in HCC, hepatitis, alcoholic liver disease, liver cell development and the metabolic functions of the liver. The aim of the present review was to summarize the most recent findings on the functions of miRNAs in the liver and discuss their potential roles in the diagnosis, prognosis and treatment of HCC.

References

Dec 20, 2002·Nature·Lisa M Coussens, Zena Werb
Sep 26, 2003·Nature·Yoontae LeeV Narry Kim
Jan 23, 2004·Nature Reviews. Cancer·Ricardo PardalSean J Morrison
Sep 17, 2004·The EMBO Journal·Yoontae LeeV Narry Kim
Nov 13, 2004·Nature·Matthew N PoyMarkus Stoffel
Mar 15, 2005·The Journal of Biological Chemistry·Qiang XieJoseph A Bonanno
Aug 4, 2005·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·E C H Lai, W Y Lau
Oct 28, 2005·The New England Journal of Medicine·Chang-Zheng Chen
Mar 25, 2006·Nature Reviews. Cancer·Aurora Esquela-Kerscher, Frank J Slack
Oct 24, 2006·Journal of Biomedicine & Biotechnology·Shi-Lung LinShao-Yao Ying
Nov 14, 2006·Nature Structural & Molecular Biology·Glen M BorchertBeverly L Davidson
Apr 27, 2007·Nature Genetics·Scott M Hammond
Jun 16, 2007·Gastroenterology·Stephanie MaXin-Yuan Guan
Jun 16, 2007·Gastroenterology·Hashem B El-Serag, K Lenhard Rudolph
Jun 26, 2007·Nature·J Graham RubyDavid P Bartel
Oct 30, 2007·Molecular Cell·Eugene BerezikovEric C Lai
Nov 13, 2007·Methods in Molecular Biology·Eugene BerezikovEdwin Cuppen
Dec 7, 2007·Cancer Research·Joanne B WeidhaasFrank J Slack
Jan 17, 2008·Nature Reviews. Genetics·Witold FilipowiczNahum Sonenberg
Mar 1, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Heike VarnholtMargarete Odenthal
Mar 1, 2008·Proceedings of the National Academy of Sciences of the United States of America·Madhu S KumarTyler Jacks
Apr 25, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yannick LadeiroJessica Zucman-Rossi
Jul 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Patrick S MitchellMuneesh Tewari
Aug 12, 2008·Biochemical and Biophysical Research Communications·Cliff Ji-Fan LinJen-Leih Wu
Sep 2, 2008·Apoptosis : an International Journal on Programmed Cell Death·Wing Pui Tsang, Tim Tak Kwok
Oct 17, 2008·The New England Journal of Medicine·Yujin HoshidaTodd R Golub
Oct 17, 2008·The New England Journal of Medicine·Morris Sherman
Oct 29, 2008·Genome Research·Robin C FriedmanDavid P Bartel
Jan 6, 2009·Journal of Cellular and Molecular Medicine·Laura GramantieriMassimo Negrini
Jan 8, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Nicholas J HandJoshua R Friedman
Jan 24, 2009·Nature Reviews. Molecular Cell Biology·V Narry KimMikiko C Siomi
Mar 20, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Wei-Chih TsaiAnn-Ping Tsou
May 15, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Teng XuShi-Mei Zhuang
May 28, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Xiaoying ZhangShuhan Sun

❮ Previous
Next ❯

Citations

Dec 19, 2017·Artificial Cells, Nanomedicine, and Biotechnology·Li-Pei WuWen-Ying Lu
Jan 13, 2018·International Journal of Molecular Medicine·Guannan WangQiang Huang
Sep 22, 2016·Cell Biochemistry and Function·Xiaogang DongWenjia Guo
May 20, 2018·Biochemical and Biophysical Research Communications·Ling HeLian-Bao Kong
Dec 4, 2020·Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology·Manar S FoudaAbdel Hady A Abdel Wahab

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenocortical Carcinoma

Hepatocellular carcinoma is the most common type of primary liver cancer and frequently occurs in individuals with chronic liver diseases like cirrhosis. Here is the latest research.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.