Function and distribution of the conjugative plasmid pLM1686 in foodborne Listeria monocytogenes in China.

International Journal of Food Microbiology
Pan MaoChangyun Ye

Abstract

Listeria monocytogenes, a fatal foodborne pathogen has the extraordinary capacity to survive in harsh conditions and is a potential threat to public health. A novel 91 kb plasmid pLM1686 was found in the prevalent L. monocytogenes sequence type (ST) 87 strain in China. In this study, the function and distribution of pLM1686 were firstly investigated in L. monocytogenes. The results showed plasmid pLM1686 had self-transmissible ability and existed in various types of L. monocytogenes isolates belonging to two lineages (lineage I and II), four serotypes (1/2b, 3b, 1/2c and 1/2a) and four STs (ST87, ST59, ST9 and ST120). The wild strain LM1686 and transconjugant strain 10403SP1686 exhibited significantly higher growth rate and biofilm formation in Modification of Welshimer's medium (MWB), greater salinity tolerance, stronger cell invasion and higher cytotoxicity than plasmid-cured strain and reference strain 10403S. Moreover, plasmid curing caused the loss of cadmium resistance of strain, and the recipient strain acquired cadmium resistance after conjugation. Thus, pLM1686 would provide L. monocytogenes advantages of surviving in adverse environments.

References

Oct 1, 1991·Applied and Environmental Microbiology·R J PremaratneE A Johnson
Feb 5, 2005·Journal of Food Protection·Andrew G Moltz, Scott E Martin
Oct 3, 2006·International Journal of Food Microbiology·Megha Gandhi, Michael L Chikindas
Jul 3, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Anders NormanSøren J Sørensen
Jul 6, 2010·Nature Reviews. Microbiology·Rachel A F Wozniak, Matthew K Waldor
Sep 9, 2010·PloS One·Carsten KuenneTrinad Chakraborty
Aug 9, 2011·Critical Reviews in Biochemistry and Molecular Biology·Finbarr Hayes, Laurence Van Melderen
Jun 27, 2013·International Journal of Food Microbiology·Sachin R KadamTjakko Abee
Jan 31, 2014·Pathogens and Disease·Yurong WenBart Devreese
Jun 25, 2015·Microbiology Spectrum·Nikolaus Goessweiner-MohrElisabeth Grohmann
Mar 19, 2016·Nature Chemical Biology·Rebecca Page, Wolfgang Peti
Jun 2, 2018·Nature Reviews. Microbiology·Giulia Pilla, Christoph M Tang
Dec 18, 2018·Frontiers in Microbiology·Florentina Ionela BucurAnca Ioana Nicolau
Apr 7, 2019·International Journal of Food Microbiology·Annabel L NaditzStephan Schmitz-Esser
Jul 25, 2019·Frontiers in Microbiology·Alexandra C KropacTaurai Tasara
Dec 13, 2019·Frontiers in Cellular and Infection Microbiology·Hossam AbdelhamedMark L Lawrence
Feb 7, 2020·Molecular Biology and Evolution·Thibault StalderEva M Top

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