Function and health status outcomes following soft tissue reconstruction for limb preservation in extremity soft tissue sarcoma

Annals of Surgical Oncology
Kristen M DavidgeA M Davis

Abstract

While advances in reconstructive surgery have facilitated limb preservation in extremity soft tissue sarcoma (ESTS), limited information exists as to the functional outcome of patients with these reconstructed extremities. The primary objective of this study is to evaluate the impact of flap reconstruction on postoperative function and health status in patients undergoing limb-salvage surgery for ESTS. Clinical and outcome data for eligible patients were extracted from a prospectively maintained database of sarcoma patients. Four outcome measures were used to assess three domains of function (impairments, activity limitations, and participation restrictions), and health status. The effect of soft tissue reconstruction on function and health status at 1-2-year follow-up was analyzed using univariate and multivariate regression. Two hundred and forty-seven patients met eligibility criteria, including 56 patients receiving flap reconstruction and 191 patients treated with primary closure. Patients receiving flaps had larger (9.8 versus 7.1 cm; P = 0.003), higher-grade (93% versus 72%; P = 0.001) tumors, and more frequently received radiotherapy (89% versus 72%; P = 0.007), and bone (20% versus 4%; P = 0.001) and motor nerve resect...Continue Reading

References

Dec 1, 1991·Journal of Surgical Oncology·R S BellV L Fornasier
Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M H RobinsonG Westbury
May 1, 1991·Cancer Causes & Control : CCC·D SerrainoC La Vecchia
Nov 1, 1991·International Journal of Radiation Oncology, Biology, Physics·S F StinsonE J Glatstein
Jun 1, 1981·Archives of Surgery·J S AbbasC P Karakousis
Jul 1, 1994·Annals of Plastic Surgery·P G CordeiroD A Hidalgo
Apr 1, 1994·Plastic and Reconstructive Surgery·B G PeatF Langer
Oct 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·A M DavisR S Bell
Dec 5, 1997·The Annals of Thoracic Surgery·T De GiacomoC Ricci
May 29, 1998·International Journal of Epidemiology·R H HarwoodS Ebrahim
Oct 17, 1998·Plastic and Reconstructive Surgery·J M SerlettiR N Rosier
Aug 17, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P J WollJ Verweij
Nov 18, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P PopovC Blomqvist
Feb 24, 2001·Medical Decision Making : an International Journal of the Society for Medical Decision Making·E W SteyerbergJ D Habbema
Sep 8, 2001·Plastic and Reconstructive Surgery·L Heller, L S Levin
Feb 14, 2002·Clinical Rehabilitation·Mieke CardolRob J de Haan
Nov 15, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A M DavisB Zee
Jun 28, 2003·International Journal of Radiation Oncology, Biology, Physics·Thomas F DeLaneyDavid C Harmon
Feb 5, 2004·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·E TukiainenR Huuhtanen
Feb 14, 2004·Stroke; a Journal of Cerebral Circulation·Jonathan W SturmAmanda G Thrift
Dec 21, 2004·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Wolfgang GreinerFrank de Charro
Jun 4, 2005·Current Opinion in Oncology·Peter C Ferguson
Aug 19, 2005·The New England Journal of Medicine·Matthew A ClarkJ Meirion Thomas
Nov 8, 2005·Archives of Physical Medicine and Rehabilitation·Alan M JetteStephen Haley
Jan 13, 2006·Plastic and Reconstructive Surgery·Andrew A NelsonE Gene Deune
Mar 16, 2006·Annals of Surgical Oncology·Grant W Carlson
May 30, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Daphne SchreiberAileen M Davis
Apr 25, 2007·Clinical Orthopaedics and Related Research·David S GellerKevin A Raskin
May 29, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Ross WilkiePeter Croft
Sep 25, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·E H C WrightH P Giele
Dec 25, 2007·Health and Quality of Life Outcomes·A Simon PickardDavid Cella

❮ Previous
Next ❯

Citations

Mar 7, 2014·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H-U SteinauL Podleska
Nov 28, 2013·La Radiologia medica·Daniela GretoGiampaolo Biti
Jul 9, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·W A TownleyS O P Hofer
Sep 13, 2012·Sarcoma·Damien GrinsellPeter F M Choong
Nov 29, 2011·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Takeshi MoriiKazuhiko Satomi
Dec 5, 2012·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Nasreen A VohraJonathan S Zager
Jun 12, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S KangH-S Kim
May 27, 2016·Journal of Surgical Oncology·William J KnausMatthew L Iorio
Oct 17, 2016·The Patient·Randall WinnetteCatherine Copley-Merriman
Jun 21, 2017·EFORT Open Reviews·E MascardA Gomez-Brouchet
Sep 7, 2018·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·G KaskE Tukiainen
Jan 16, 2019·Journal of Surgical Oncology·Kelly M BridghamJustin M Sacks
Mar 1, 2013·Proceedings. Biological Sciences·Xi-Ping DongPhilip C J Donoghue
Jun 29, 2018·Journal of Surgical Oncology·Simone WiggeHans-Georg Kopp
Jan 3, 2019·The Journal of the American Academy of Orthopaedic Surgeons·Matthew T HoudekPeter C Ferguson
Apr 15, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Allison J L'HottaAllison A King
Apr 14, 2017·World Journal of Surgical Oncology·Lars Erik PodleskaGeorg Taeger
Jan 18, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Sabrina KraussJonas Kolbenschlag
Nov 26, 2020·Annals of Plastic Surgery·David P PerraultAlex K Wong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.

© 2021 Meta ULC. All rights reserved