Function of redox-active tyrosine in photosystem II

Biophysical Journal
Hiroshi Ishikita, Ernst-Walter Knapp

Abstract

Water oxidation at photosystem II Mn-cluster is mediated by the redox-active tyrosine Y(Z). We calculated the redox potential (E(m)) of Y(Z) and its symmetrical counterpart Y(D), by solving the linearized Poisson-Boltzmann equation. The calculated E(m)(Y( )/Y(-)) were +926 mV/+694 mV for Y(Z)/Y(D) with the Mn-cluster in S2 state. Together with the asymmetric position of the Mn-cluster relative to Y(Z/D), differences in H-bond network between Y(Z) (Y(Z)/D1-His(190)/D1-Asn(298)) and Y(D) (Y(D)/D2-His(189)/D2-Arg(294)/CP47-Glu(364)) are crucial for E(m)(Y(Z/D)). When D1-His(190) is protonated, corresponding to a thermally activated state, the calculated E(m)(Y(Z)) was +1216 mV, which is as high as the E(m) for P(D1/D2). We observed deprotonation at CP43-Arg(357) upon S-state transition, which may suggest its involvement in the proton exit pathway. E(m)(Y(D)) was affected by formation of P(D2)(+) (but not P(D1)(+)) and sensitive to the protonation state of D2-Arg(180). This points to an electrostatic link between Y(D) and P(D2).

References

Apr 2, 1968·Biochimica Et Biophysica Acta·P JoliotB Kok
Dec 31, 1982·Biochemical and Biophysical Research Communications·A Boussac, A L Etienne
Mar 10, 1998·European Journal of Biochemistry·P MannaW Vermaas
Apr 27, 1999·Biochimica Et Biophysica Acta·M Haumann, W Junge
Jul 22, 1999·Biochemistry·C TommosP L Dutton
May 17, 2000·Biochimica Et Biophysica Acta·C Tommos, G T Babcock
Jun 21, 2001·Journal of the American Chemical Society·D M PopovićE W Knapp
Jan 5, 2002·Proceedings of the National Academy of Sciences of the United States of America·P FallerA Boussac
Apr 4, 2002·Journal of the American Chemical Society·Dragan M PopovićErnst-Walter Knapp
Jun 26, 2002·Biochemistry·Fabrice RappaportJérôme Lavergne
Sep 12, 2002·Annual Review of Plant Biology·Bruce A Diner, Fabrice Rappaport
Sep 17, 2003·The Journal of Biological Chemistry·Philipp Voigt, Ernst-Walter Knapp
Feb 7, 2004·Science·Kristina N FerreiraSo Iwata
Mar 20, 2004·Science·A W Rutherford, A Boussac
Apr 22, 2004·Biochimica Et Biophysica Acta·A William RutherfordPeter Faller
Aug 18, 2004·Current Opinion in Structural Biology·So Iwata, James Barber
Mar 9, 2005·Biochemistry·Hiroshi IshikitaErnst-Walter Knapp
Oct 20, 2005·Journal of the American Chemical Society·Hiroshi Ishikita, Ernst-Walter Knapp
Nov 1, 2005·Biophysical Journal·Hiroshi IshikitaErnst-Walter Knapp
Nov 9, 2005·Biochemistry·Hiroshi Ishikita, Ernst-Walter Knapp
May 6, 1994·Science·M A SteffenS G Boxer
Apr 30, 1998·The Journal of Physical Chemistry. B·A D MacKerellM Karplus

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Citations

Jul 27, 2007·Cell Biochemistry and Biophysics·Kvetoslava Burda
Nov 15, 2007·Chemical Reviews·My Hang V Huynh, Thomas J Meyer
Jun 19, 2012·Chemical Reviews·David R WeinbergThomas J Meyer
Apr 20, 2013·Proceedings of the National Academy of Sciences of the United States of America·Keisuke SaitoHiroshi Ishikita
Nov 29, 2013·Journal of the Royal Society, Interface·Hiroshi Ishikita, Keisuke Saito
Apr 17, 2012·Biochimica Et Biophysica Acta·Ana-Nicoleta Bondar, Holger Dau
Nov 25, 2006·Biochimica Et Biophysica Acta·Hiroshi IshikitaErnst-Walter Knapp
Feb 12, 2019·Nature·Thomas G LaughlinKaren M Davies
Jan 9, 2010·European Journal of Social Psychology·Michelle N Shiota, Douglas T Kenrick
Aug 12, 2020·Chemical Society Reviews·Young Jin SaYun Jeong Hwang
Oct 18, 2019·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Ishita PalSomdatta Ghosh Dey
Apr 17, 2020·Photosynthesis Research·Nicoletta LiguoriSebastian Thallmair
Jul 1, 2008·Journal of Chemical Theory and Computation·Francesca CostanzoMichiel Sprik
Nov 10, 2006·Chemical Reviews·James P McEvoy, Gary W Brudvig
Aug 3, 2011·Journal of the American Chemical Society·Keisuke SaitoHiroshi Ishikita
Aug 16, 2018·The Journal of Physical Chemistry. B·Hernan BiavaPeter Hildebrandt
Dec 31, 2020·The Journal of Physical Chemistry. B·Clorice R ReinhardtSharon Hammes-Schiffer
Jul 18, 2018·Biochemistry·Keisuke KawashimaHiroshi Ishikita
Nov 16, 2019·The Journal of Physical Chemistry Letters·Manoj MandalHiroshi Ishikita

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