Function of smooth muscle of the rat renal pelvis--response of the isolated pelvis muscle to angiotensin and some other substances

British Journal of Pharmacology
J P Finberg, W S Peart


1. The circular component of the renal pelvis muscle of the rat appears as an intact band around the tip of the papilla.2. The isolated pelvis muscle strip showed spontaneous rhythmic contractions in Locke solution at 38 degrees C. The rate of contractions corresponded with the rate of pressure fluctuations recorded during free-flow from a ureteral catheter inserted up to the renal hilum of anaesthetized rats.3. Angiotensin and adrenaline (13 ng/ml) produced a rise in tone of the isolated pelvis muscle, and an increase in the rate of spontaneous contractions; noradrenaline produced mainly an increase in the amplitude and rate of spontaneous contractions. Angiotensin and noradrenaline injected intravenously also produced an increased rate of pressure fluctuations recorded from the ureteral catheter.4. Acetylcholine, nicotine and 5-hydroxytryptamine had no effect on the isolated tissue, but isoprenaline was capable of causing a decrease, and tyramine an increase, in the rate of spontaneous contractions in high dose (0.33 mug/ml).5. An increase in the tone of the circular pelvis muscle could lead to a reversible obstruction of urine outflow from the kidney.


Jun 1, 1970·British Journal of Pharmacology·J P Finberg, W S Peart
Jun 1, 1948·The American Journal of Physiology·R P AHLQUIST
Jan 1, 1951·The Journal of the Faculty of Radiologists·J O Y COLE

❮ Previous
Next ❯


Mar 1, 1979·The American Journal of Anatomy·E R Lacy, B Schmidt-Nielsen
Jan 1, 1974·Pflügers Archiv : European journal of physiology·J Hannappel, K Golenhofen
Apr 4, 1974·Pflügers Archiv : European journal of physiology·J Hannappel, K Golenhofen
Sep 1, 1971·European Journal of Pharmacology·J A Gosling, A N Waas
Dec 1, 1974·European Journal of Pharmacology·M ToniniA Crema
Dec 1, 1975·European Journal of Pharmacology·N Longrigg
Apr 24, 1981·European Journal of Pharmacology·M Del TaccaC Bernardini
Feb 28, 2002·British Journal of Pharmacology·D S HauserH Danuser
Oct 1, 1972·British Journal of Urology·J A Gosling, J S Dixon
Aug 1, 1974·British Journal of Urology·N Longrigg
Jun 1, 1970·British Journal of Pharmacology·J P Finberg, W S Peart
Oct 24, 2000·Kidney International·H FujinakaI Ichikawa
Jan 9, 2010·Journal of the American Society of Nephrology : JASN·Kirsten MadsenBoye L Jensen
Jan 1, 1974·Naunyn-Schmiedeberg's Archives of Pharmacology·M Del TaccaA Crema
Aug 1, 1978·Urology·R M Weiss
Feb 16, 2016·Clinical and Experimental Pharmacology & Physiology·Michael J NguyenRichard J Lang
Feb 1, 1973·The Anatomical Record·J S Dixon, J A Gosling
Apr 1, 1971·The American Journal of Anatomy·J A Gosling, J S Dixon
Sep 1, 1975·The Journal of Urology·N Longrigg
Jan 1, 1988·International Urology and Nephrology·F AragonaG Passerini
Apr 1, 1982·British Journal of Clinical Pharmacology·J N Longrigg

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pflügers Archiv : European journal of physiology
K Golenhofen, J Hannappel
British Journal of Pharmacology
R J AncillP H Redfern
Naunyn-Schmiedeberg's Archives of Pharmacology
M Del TaccaA Crema
© 2021 Meta ULC. All rights reserved