PMID: 11607542May 9, 1995Paper

Function of the oxidative burst in hypersensitive disease resistance

Proceedings of the National Academy of Sciences of the United States of America
R. TenhakenC Lamb

Abstract

Microbial elicitors or attempted infection with an avirulent pathogen strain causes the rapid production of reactive oxygen intermediates. Recent findings indicate that H2O2 from this oxidative burst plays a central role in the orchestration of the hypersensitive response: (i) as the substrate driving the cross-linking of cell wall structural proteins to slow microbial ingress prior to the deployment of transcription-dependent defenses and to trap pathogens in cells destined to undergo hypersensitive cell death, (ii) as a local threshold trigger of this programmed death in challenged cells, and (iii) as a diffusible signal for the induction in adjacent cells of genes encoding cellular protectants such as glutathione S-transferase and glutathione peroxidase. These findings provide the basis for an integrated model for the orchestration of the localized hypersensitive resistance response to attack by an avirulent pathogen.

References

Nov 1, 1991·The Plant Journal : for Cell and Molecular Biology·J ShengM C Mehdy
Jan 1, 1990·Annual Review of Genetics·N T Keen
Oct 22, 1993·Cell·D M HockenberyS J Korsmeyer
Sep 13, 1994·Proceedings of the National Academy of Sciences of the United States of America·J Glazebrook, F M Ausubel
Feb 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·K BerhaneB Mannervik
Aug 1, 1993·Trends in Microbiology·W P LindsayR A Dixon
May 20, 1994·Cell·R A DietrichJ L Dangl
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·J T Greenberg, F M Ausubel
Aug 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·D AlexanderE Ward

❮ Previous
Next ❯

Citations

Apr 21, 2005·Journal of Chemical Ecology·Steven D Allison, Jack C Schultz
Apr 2, 2005·Methods in Cell Science : an Official Journal of the Society for in Vitro Biology·Isak B Gerber, Ian A Dubery
Jan 1, 2010·Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology·Rohit JoshiPramod Kumar
Mar 6, 1999·Current Opinion in Plant Biology·D Scheel
Nov 7, 2000·Journal of Inorganic Biochemistry·M E Vol'pinA A Aver'yanov
Mar 17, 2000·Biochimica Et Biophysica Acta·J Hernández-RuizM B Arnao
Jan 1, 1997·Free Radical Biology & Medicine·C R McClung
Apr 17, 1999·The Plant Journal : for Cell and Molecular Biology·A TakahashiK Shimamoto
Apr 22, 2011·Proceedings of the National Academy of Sciences of the United States of America·Aizhong CaoPeidu Chen
Mar 24, 2007·Molecular Plant-microbe Interactions : MPMI·Ramani S RaviralaMichael J D San Francisco
Jul 3, 2007·Molecular Plant-microbe Interactions : MPMI·Il-Pyung AhnSeok-Cheol Suh
Apr 3, 2004·Genome Génome / Conseil National De Recherches Canada·Nadim AlkharoufBenjamin Matthews
Jan 5, 2006·Genome Génome / Conseil National De Recherches Canada·Wenchun ZhouDean E Riechers
Jun 1, 1996·Annual Review of Plant Physiology and Plant Molecular Biology·Kathleen A. Marrs
Jun 1, 1997·Annual Review of Plant Physiology and Plant Molecular Biology·Chris Lamb, Richard A. Dixon
Sep 21, 2004·Annual Review of Plant Biology·Klaus Apel, Heribert Hirt
Jan 1, 1996·Annual Review of Phytopathology·H Sandermann
Jan 1, 1997·Annual Review of Phytopathology·L SticherJ P Métraux
Mar 12, 2004·Annual Review of Phytopathology·S W Hutcheson
Dec 1, 2000·Biochemical and Biophysical Research Communications·G K AgrawalN S Jwa
Sep 15, 1999·Proceedings of the National Academy of Sciences of the United States of America·T KawasakiK Shimamoto
Dec 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·D B JenningsJ D Williamson
Aug 16, 2011·Annual Review of Phytopathology·Richard A Dixon

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.