PMID: 6971072Jan 1, 1981Paper

Functional activity of T- and B-lymphocyte populations after rubomycin and carminomycin exposure

Antibiotiki
A E Vatin

Abstract

The dynamics of antibody genesis at various periods after single administrations of the antibiotics to mice and the mice spleen capacity to cooperate with intact T- and B- lymphocytes and macrophages in an immune response to sheep red cells were studied. It was found that rubomycin in equal with carminomycin doses by the toxicity induced more significant and slower reducing shifts in the immune response. Analysis of the cell mechanism of the immunosuppressive effects of rubomycin and carminomycin at early periods after their administration showed that the antibiotics inhibited mainly the functional activity of B-lymphocytes and had not effect on the helper function of T-lymphocytes. The immunological activity of macrophages was inhibited insignificantly.

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.