Functional analyses in the hemipteran Oncopeltus fasciatus reveal conserved and derived aspects of appendage patterning in insects

Developmental Biology
David R Angelini, Thomas C Kaufman

Abstract

The conservation of expression of appendage patterning genes, particularly Distal-less, has been shown in a wide taxonomic sampling of animals. However, the functional significance of this expression has been tested in only a few organisms. Here we report functional analyses of orthologues of the genes Distal-less, dachshund, and homothorax in the appendages of the milkweed bug Oncopeltus fasciatus (Hemiptera). This hemimetabolous insect has typical legs but highly derived mouthparts. Distal-less, dachshund, and homothorax are conserved in their individual expression patterns and functions in the legs of Oncopeltus, but their functions in other appendages are in some cases divergent. We find that specification of antennal identity does not require wild-type Distal-less activity in Oncopeltus as it does in Drosophila. Additionally, the mouthparts of Oncopeltus show novel patterns of gene expression and function, relative to other insects. Expression of Distal-less in the maxillary stylets of Oncopeltus does not seem necessary for proper development of this appendage, while dachshund and homothorax are crucial for formation of the mandibular and maxillary stylets. These data are used to evaluate hypotheses for the evolution of he...Continue Reading

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Citations

May 20, 2009·Proceedings of the National Academy of Sciences of the United States of America·Armin P Moczek, Debra J Rose
Nov 2, 2012·EvoDevo·Joshua F Coulcher, Maximilian J Telford
Mar 5, 2005·Development Genes and Evolution·Ying Dong, Markus Friedrich
May 17, 2008·Development Genes and Evolution·William SewellLisa Nagy
Apr 30, 2010·Development Genes and Evolution·Brigid C O'Donnell, Elizabeth L Jockusch
Jul 15, 2015·Proceedings of the National Academy of Sciences of the United States of America·Yu MatsuuraTakema Fukatsu
Oct 8, 2015·Molecular Biology and Evolution·Natascha TuretzekNikola-Michael Prpic
Dec 21, 2010·Insect Biochemistry and Molecular Biology·Ryo FutahashiTakema Fukatsu
Dec 19, 2015·BMC Evolutionary Biology·Ariel D Chipman
Nov 22, 2008·Evolution & Development·Steven HrycajAleksandar Popadić
Sep 29, 2012·Evolution & Development·Michael BirkanAriel D Chipman
May 4, 2011·Evolution & Development·Franck Simonnet, Armin P Moczek
Nov 2, 2014·Ecology and Evolution·Emily R Burdfield-Steel, David M Shuker
Jun 29, 2011·Developmental Biology·Nataliya TurchynAleksandar Popadić
Jul 24, 2015·Proceedings. Biological Sciences·Alexander BlankeBernhard Misof
Nov 16, 2005·Annual Review of Genetics·David R Angelini, Thomas C Kaufman
May 12, 2010·Developmental Biology·Nina D SchaeperErnst A Wimmer
May 8, 2015·Proceedings. Biological Sciences·Prashant P SharmaCassandra G Extavour
Dec 9, 2008·Developmental Biology·David R AngeliniElizabeth L Jockusch
Feb 8, 2006·Developmental Biology·Kristen A PanfilioThomas C Kaufman
Sep 27, 2005·Developmental Biology·David R AngeliniThomas C Kaufman
Nov 7, 2006·Developmental Biology·Richard B EmmonsIan Duncan
Aug 23, 2005·Developmental Biology·David R Angelini, Thomas C Kaufman

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