PMID: 8961874Dec 1, 1996Paper

Functional analyses of the stratum corneum in scars. Sequential studies after injury and comparison among keloids, hypertrophic scars, and atrophic scars

Archives of Dermatology
T SuetakeH Tagami

Abstract

To characterize the functional properties of the stratum corneum (SC) of various scars. A prospective cohort study. University hospital medical center. Thirty-two consecutive patients surgically treated for various skin diseases and 26 consecutive patients with hypertrophic scars or keloids. Noninvasive bioengineering measurements of functional properties of the SC, such as transepidermal water loss (TEWL), high-frequency conductance, and SC turnover time. The SC barrier function assessed by TEWL was found to be a better parameter for the functional evaluation of scars than the hydration state of the skin surface measured by high-frequency conductometry. In general, the SC on the scars of deeper wounds in the dermis took longer to normalize functionally than the SC on the scars of superficial wounds, especially on the high compared with the abdomen. Thus, elevated levels of TEWL observed on scars at the donor sites of split-thickness grafts normalized between 200 and 400 days in contrast to fewer than 50 days for those of subepidermal erosions. Both TEWL and high-frequency conductance remained high in hypertrophic scars and keloids, and the SC involved showed a faster turnover time than that of adjacent normal skin. Scars, a pr...Continue Reading

Citations

Nov 5, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Oliver J Smith, Duncan Angus McGrouther
Apr 25, 2000·Biochemical and Biophysical Research Communications·S TodaH Sugihara
Oct 31, 2007·Aesthetic Plastic Surgery·Thomas A Mustoe
Mar 15, 2003·Clinics in Plastic Surgery·Shahrad R Rahban, Warren L Garner
Apr 20, 2001·Burns : Journal of the International Society for Burn Injuries·E Van den KerckhoveJ De Cubber
May 31, 2001·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·C G McOwanJ Wilton
Sep 24, 1998·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·R Ghadially
Feb 14, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Dolores WolframHildegunde Piza-Katzer
May 21, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Arnold LeeEllen Marmur
Jul 2, 2010·Nutrition Reviews·Angela C B FerreiraLydia M Ferreira
May 4, 2006·The Journal of Clinical Investigation·Julia A Segre
Jul 16, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Khalifa E Sharquie, Muhsin A Al-Dhalimi
Nov 7, 2006·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·You Jeong KimYoung Min Park
Mar 22, 2014·Journal of Pharmaceutical Sciences·Prashanth MandaS Narasimha Murthy
Jan 5, 2002·The Journal of Investigative Dermatology. Symposium Proceedings·H TagamiK Kikuchi
May 22, 2010·Burns : Journal of the International Society for Burn Injuries·Nele BrusselaersStan Monstrey
Jan 19, 2010·Burns : Journal of the International Society for Burn Injuries·Haejun YimJong Hyun Kim
Nov 15, 2013·The Journal of Investigative Dermatology·Wei XuSeok J Hong
Aug 2, 2008·Burns : Journal of the International Society for Burn Injuries·Mahnoush MomeniHamid Karimi
Nov 24, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Rei OgawaChiyomi Nakao
Sep 23, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Kristina D O'ShaughnessyThomas A Mustoe
Jul 22, 2008·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Oliver KloetersThomas A Mustoe
Sep 10, 2008·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Oliver KloetersThomas A Mustoe
Jan 9, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Sadanori AkitaAkiyoshi Hirano
Oct 22, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Keiichi SugataYoshinori Takema
Sep 22, 2012·International Journal of Cosmetic Science·A V RawlingsK J Lombard
Mar 9, 2011·International Journal of Cosmetic Science·A M Kligman
Aug 10, 2013·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jong-Kyung YoumPeter M Elias
Jan 26, 2011·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Walaiorn PratchyapruitHachiro Tagami
Aug 4, 2011·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Thomas A Mustoe, Anandev Gurjala
Apr 20, 2006·Burns : Journal of the International Society for Burn Injuries·Sadanori AkitaAkiyoshi Hirano
Jun 4, 2014·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Stan MonstreyLuc Téot
Jul 20, 2014·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Martin HellströmUlf Bertheim
May 4, 2013·Burns : Journal of the International Society for Burn Injuries·Henk HoeksemaStan Monstrey
Aug 31, 2016·Burns and Trauma·Kwang Chear LeeNaiem Moiemen
May 29, 2016·Burns : Journal of the International Society for Burn Injuries·Kim L M GardienEsther Middelkoop
Mar 13, 2016·Dermatologic Therapy·Veronika ĎurčanskáVladimír Vašků
Jul 6, 2016·The British Journal of Dermatology·G C LimandjajaS Gibbs
Nov 15, 2016·The Journal of Investigative Dermatology·Jingling ZhaoSeok Jong Hong

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