Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Isabelle AudoMichel Paques

Abstract

To report functional and high-resolution retinal imaging abnormalities, including adaptive optics (AO) throughout the course of acute macular neuroretinopathy (AMNR). Two female patients (four eyes) with a diagnosis of AMNR were observed at the Clinical Investigation Center, CHNO des Quinze-Vingts, Paris, France. The patients underwent detailed ophthalmic examination including best-corrected visual acuity, slit-lamp examination, kinetic and static perimetry, full-field and multifocal electroretinogram, infrared reflectance, autofluorescence imaging and spectral-domain optical coherence tomography (SD-OCT) and AO fundus imaging at presentation and during follow-up. Both cases showed concomitant loss of integrity of the outer retinal structures on SD-OCT, and marked abnormalities on AO imaging with disruption of the visibility of the cone mosaic. In the first case, photoreceptor damage was seen to progress during several weeks before healing. In both cases, there were persistent morphological abnormalities of photoreceptors 1 year after onset. This study further highlights the value of AO fundus imaging to facilitate detection, mapping, and monitoring of damage to the cone outer segments during AMNR. In particular, residual damag...Continue Reading

References

Oct 1, 1975·American Journal of Ophthalmology·P J Bos, A F Deutman
Feb 1, 1989·Ophthalmology·M H MillerA C Bird
Sep 1, 1987·Documenta Ophthalmologica. Advances in Ophthalmology·J S StilmaF C Crezee
Apr 1, 1984·The British Journal of Ophthalmology·P A SievingM F Rabb
Aug 1, 1993·Archives of Ophthalmology·U R DesaiS Natarajan
Nov 14, 1997·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J LiangD T Miller
Jan 28, 1998·Archives of Ophthalmology·P Amin, T A Cox
Feb 13, 2001·Acta Ophthalmologica Scandinavica·B Feigl, A Haas
Feb 28, 2002·American Journal of Ophthalmology·Arnd Gandorfer, Michael W Ulbig
Mar 9, 2002·Retina·Manuel Gómez-TorreiroM José Rodriguez-Cid
Feb 1, 2003·Survey of Ophthalmology·Sean D TurbevilleJ Donald M Gass
Jul 16, 2003·Archives of Ophthalmology·Raj K MaturiDerek T Sprunger
Sep 26, 2003·Investigative Ophthalmology & Visual Science·Aristofanis PallikarisHeidi Hofer
Oct 15, 2003·Archives of Ophthalmology·Andrew C BrowningWinfried M Amoaku
Mar 25, 2006·Journal français d'ophtalmologie·A Kuznik-BorkowskaA Gaudric
Aug 24, 2006·Clinical & Experimental Ophthalmology·Alireza MirshahiHolger Baatz
Sep 19, 2006·Eye·H D CorverB P Leroy
Dec 21, 2006·The British Journal of Ophthalmology·B K MonsonJ S Duker
Nov 1, 2007·Documenta Ophthalmologica. Advances in Ophthalmology·Donald C HoodAnja M Palmowski-Wolfe
Nov 28, 2008·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Toco Yuen ChuiStephen A Burns
Mar 4, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Irmingard M NeuhannFaik Gelisken
Nov 26, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Célia MaschiPierre Gastaud
Feb 22, 2011·Retina·Sushma K VanceMichael J Cooney
Oct 20, 2011·Acta Ophthalmologica·Inger C MunchMichael Larsen
May 23, 2012·European Journal of Ophthalmology·Georges AzarMartine Mauget-Faÿsse
Apr 26, 2013·Retina·Sean O HansenDavid V Weinberg
Nov 26, 2014·Ophthalmic Surgery, Lasers & Imaging Retina·Sarah MrejenK Bailey Freund

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Citations

May 14, 2016·The British Journal of Ophthalmology·Marion R MunkMartin S Zinkernagel

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