Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading

Journal of Applied Physiology
Eline OppersmaC S Bruells

Abstract

Assessment of diaphragmatic effort is challenging, especially in critically ill patients in the phase of weaning. Fractional thickening during inspiration assessed by ultrasound has been used to estimate diaphragm effort. It is unknown whether more sophisticated ultrasound techniques such as speckle tracking are superior in the quantification of inspiratory effort. This study evaluates the validity of speckle tracking ultrasound to quantify diaphragm contractility. Thirteen healthy volunteers underwent a randomized stepwise threshold loading protocol of 0-50% of the maximal inspiratory pressure. Electric activity of the diaphragm and transdiaphragmatic pressures were recorded. Speckle tracking ultrasound was used to assess strain and strain rate as measures of diaphragm tissue deformation and deformation velocity, respectively. Fractional thickening was assessed by measurement of diaphragm thickness at end-inspiration and end-expiration. Strain and strain rate increased with progressive loading of the diaphragm. Both strain and strain rate were highly correlated to transdiaphragmatic pressure (strain r2 = 0.72; strain rate r2 = 0.80) and diaphragm electric activity (strain r2 = 0.60; strain rate r2 = 0.66). We conclude that spe...Continue Reading

References

Sep 1, 1990·The Journal of Physiology·S C GandeviaB L Plassman
Jul 1, 1997·Journal of Applied Physiology·D CohnF D McCool
Aug 13, 1998·The European Respiratory Journal·R C ChenS Yan
Nov 9, 2000·American Journal of Respiratory and Critical Care Medicine·W D Reid, A N Belcastro
Nov 24, 2001·American Journal of Respiratory and Critical Care Medicine·M Orozco-LeviJ Gea
Jan 16, 2002·American Journal of Respiratory and Critical Care Medicine·Satoru EbiharaBasil J Petrof
Mar 28, 2002·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·J D'hoogeG R Sutherland
Aug 21, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society/European Respiratory Society
Nov 2, 2002·American Journal of Respiratory and Critical Care Medicine·Franco LaghiMartin J Tobin
Mar 31, 2007·Journal of Applied Physiology·Sairam ParthasarathyMartin J Tobin
Mar 28, 2008·The New England Journal of Medicine·Sanford LevineJoseph B Shrager
Dec 6, 2008·Ultrasound in Medicine & Biology·Jonas CrosbyHans Torp
Apr 25, 2009·Journal of Applied Physiology·David K McKenzieSimon C Gandevia
Jun 25, 2009·Critical Care : the Official Journal of the Critical Care Forum·Annalisa CarlucciStefano Nava
Jul 3, 2010·Critical Care : the Official Journal of the Critical Care Forum·Greet HermansGhislaine Gayan-Ramirez
Sep 4, 2010·American Journal of Respiratory and Critical Care Medicine·Samir JaberStefan Matecki
Oct 1, 2011·American Journal of Respiratory and Critical Care Medicine·Jonne DoorduinLeo M A Heunks
Apr 6, 2012·Intensive Care Medicine·Emmanuel VivierLaurent Brochard
Sep 26, 2012·Circulation. Cardiovascular Imaging·Teerapat YingchoncharoenThomas H Marwick
Oct 30, 2012·American Journal of Respiratory and Critical Care Medicine·Jonne DoorduinLeo M A Heunks
Jan 25, 2013·Intensive Care Medicine·Dimitrios MatamisLaurent Brochard
Mar 22, 2014·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·N HatamC S Bruells
Dec 30, 2014·Current Opinion in Critical Care·Leo M A HeunksJohannes G van der Hoeven
Mar 12, 2015·American Journal of Respiratory and Critical Care Medicine·Pleuni E HooijmanCoen A C Ottenheijm
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Michele UmbrelloGaetano Iapichino
Jul 15, 2015·American Journal of Respiratory and Critical Care Medicine·Ewan C GoligherNiall D Ferguson
Oct 29, 2015·European Heart Journal·Otto A SmisethStig Urheim
Jul 28, 2016·BMC Anesthesiology·Sam R OrdeHiroshi Sekiguchi
Feb 25, 2017·Journal of the American College of Cardiology·Patrick CollierAllan Klein

❮ Previous
Next ❯

Citations

Dec 14, 2018·The European Respiratory Journal·Raquel Guimarães-CostaUNKNOWN contributors to the RespiStimALS study were:
May 6, 2019·BMC Musculoskeletal Disorders·Lars Henrik FrichAnders Holsgaard-Larsen
May 3, 2019·American Journal of Physiology. Cell Physiology·Robbert J van der PijlCoen A C Ottenheijm
Jul 7, 2018·Journal of Cachexia, Sarcopenia and Muscle·Robbert van der PijlCoen Ottenheijm
Jul 2, 2020·World Journal of Clinical Cases·Alain BoussugesFabienne Brégeon
Dec 27, 2019·Current Opinion in Critical Care·Martin Dres, Alexandre Demoule
Nov 29, 2020·Critical Care : the Official Journal of the Critical Care Forum·Quentin FosséMartin Dres
Mar 17, 2021·BMC Pulmonary Medicine·Franco A LaghiHameeda Shaikh
Oct 15, 2020·Muscle & Nerve·Juerd Wijntjes, Nens van Alfen
Jun 4, 2021·Pediatric Pulmonology·Mark D WeberJan Hau Lee
Aug 4, 2021·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Guillaume FossatThierry Boulain
Sep 3, 2021·Journal of Applied Physiology·Diana JansenLeo Heunks
Apr 18, 2021·The European Respiratory Journal·Jeroen L M van DoornJonne Doorduin

❮ Previous
Next ❯

Software Mentioned

SPSS
ST
GE
Matlab
EchoPac Q

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.